Linked Life Data

19481180

Source:http://linkedlifedata.com/resource/pubmed/id/19481180

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PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2009-10-16
pubmed:abstractText
Inflight 24-h profiles of blood pressure (BP) and heart rate (HR) were recorded in 2 ESA-astronauts by automatic upper arm cuff measurements. In one astronaut this was combined with Portapres continuous finger blood pressure recordings. It was the intention to contrast the latter to 24-h recordings in an earlier Head-Down-Tilted (HDT) bed rest study [Voogel, A.J., Stok, W.J., Pretorius, P.J., Van Montfrans, G.A., Langewouters, G.J., Karemaker, J.M., 1997. Circadian blood pressure and systemic haemodynamics during 42 days of 6 degrees head-down tilt. Acta Physiol. Scand. 161, pp. 71-80]. BP-levels in Space were not very much changed from preflight; the circadian BP-rhythm seemed dampened. Only daytime diastolic pressures (both subjects) and nighttime HR (one subject) were significantly lower in Space. However, compared to the effect of a control tilt manoeuvre on the ground, even lower BP values might have been expected. Striking were the BP- and HR-surges during the working days in Space, often related to stressful moments like live appearances on public TV. Systemic vascular resistance (SVR) dropped during the night, unlike HDT. Thus, actual spaceflight refuted our earlier findings in HDT both for BP-levels and for daytime to nighttime changes. The combined observations lead to the hypothesis that short-lasting spaceflight may induce strong psychological stress in astronauts. When interpreting space-physiological observations this must be taken into account.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1878-1519
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
169 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S55-8
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
24-h blood pressure in Space: The dark side of being an astronaut.
pubmed:affiliation
Department of Systems Physiology, Academic Medical Center at the University of Amsterdam, The Netherlands. j.m.karemaker@amc.uva.nl
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't