Source:http://linkedlifedata.com/resource/pubmed/id/19477462
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2-3
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pubmed:dateCreated |
2009-7-7
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pubmed:abstractText |
An 8-year-old crossbred dog was presented with a one-month history of progressive weakness, respiratory impairment and abdominal distension. Surgical exploration revealed the presence of a splenic mass that infiltrated the mesentery and was adherent to the stomach and pancreas. The mass was composed of highly cellular areas of spindle-shaped cells arranged in interlacing bundles, streams, whorls and storiform patterns (Antoni A pattern) and less cellular areas with more loosely arranged spindle to oval cells (Antoni B pattern). The majority of neoplastic cells expressed vimentin, S-100 and glial fibrillary acidic protein (GFAP), but did not express desmin, alpha-smooth muscle actin or factor VIII. These morphological and immunohistochemical findings characterized the lesion as a malignant peripheral nerve sheath tumour (PNST). Primary splenic PNST has not been documented previously in the dog.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1532-3129
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
141
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
195-8
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pubmed:dateRevised |
2010-4-28
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pubmed:meshHeading |
pubmed-meshheading:19477462-Animals,
pubmed-meshheading:19477462-Dog Diseases,
pubmed-meshheading:19477462-Dogs,
pubmed-meshheading:19477462-Euthanasia, Animal,
pubmed-meshheading:19477462-Fatal Outcome,
pubmed-meshheading:19477462-Female,
pubmed-meshheading:19477462-Glial Fibrillary Acidic Protein,
pubmed-meshheading:19477462-Immunohistochemistry,
pubmed-meshheading:19477462-Nerve Sheath Neoplasms,
pubmed-meshheading:19477462-S100 Proteins,
pubmed-meshheading:19477462-Splenic Neoplasms,
pubmed-meshheading:19477462-Tumor Markers, Biological,
pubmed-meshheading:19477462-Vimentin
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pubmed:articleTitle |
Primary splenic peripheral nerve sheath tumour in a dog.
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pubmed:affiliation |
Institute of Animal Pathology, Vetsuisse Faculty, University of Berne, Switzerland.
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pubmed:publicationType |
Journal Article,
Case Reports
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