Source:http://linkedlifedata.com/resource/pubmed/id/19473447
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
|
pubmed:dateCreated |
2009-8-19
|
pubmed:abstractText |
Actinic cheilitis (AC) is an oral pre-cancerous lesion that sometimes develops into lip squamous cell carcinoma (SCC). Syndecan-1, a transmembrane heparan sulfate proteoglycan, modulates cell-proliferation, adhesion, migration and angiogenesis. Malignant epithelial cells often down-regulate their own syndecan-1 production, and are capable of inducing aberrant syndecan-1 expression in stromal cells. The aim of this study was to evaluate the variations in syndecan-1 expression during lip carcinogenesis, in normal lip (NL), AC and well-differentiated lip SCC.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
D
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
1600-0714
|
pubmed:author | |
pubmed:issnType |
Electronic
|
pubmed:volume |
38
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
580-3
|
pubmed:meshHeading |
pubmed-meshheading:19473447-Adult,
pubmed-meshheading:19473447-Aged,
pubmed-meshheading:19473447-Aged, 80 and over,
pubmed-meshheading:19473447-Carcinoma, Squamous Cell,
pubmed-meshheading:19473447-Case-Control Studies,
pubmed-meshheading:19473447-Cheilitis,
pubmed-meshheading:19473447-Female,
pubmed-meshheading:19473447-Humans,
pubmed-meshheading:19473447-Keratosis, Actinic,
pubmed-meshheading:19473447-Lip,
pubmed-meshheading:19473447-Lip Neoplasms,
pubmed-meshheading:19473447-Male,
pubmed-meshheading:19473447-Middle Aged,
pubmed-meshheading:19473447-Reference Values,
pubmed-meshheading:19473447-Syndecan-1,
pubmed-meshheading:19473447-Tumor Markers, Biological
|
pubmed:year |
2009
|
pubmed:articleTitle |
Reduction of syndecan-1 expression during lip carcinogenesis.
|
pubmed:affiliation |
Department of Oral Pathology, School of Dentistry, University of Concepción, Casilla 2236, Concepción, Chile. almartin@udec.cl
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|