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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2009-7-27
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pubmed:abstractText |
A single nucleotide polymorphism in the 3'-untranslated region of the progranulin gene (GRN; 3'UTR+78C>T; rs5848) was reported to alter the risk for frontotemporal lobar degeneration with ubiquitin-positive inclusions (FTLD-U). rs5848 is located within a micro-RNA binding site and affects the expression of GRN.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1468-1331
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pubmed:author |
pubmed-author:BakerMM,
pubmed-author:BarcikowskaMM,
pubmed-author:CzyzewskiKK,
pubmed-author:FarrerM JMJ,
pubmed-author:Jasinska-MygaBB,
pubmed-author:Krygowska-WajsAA,
pubmed-author:OpalaGG,
pubmed-author:RademakersRR,
pubmed-author:RossO AOA,
pubmed-author:UittiR JRJ,
pubmed-author:WiderCC,
pubmed-author:WszolekZ KZK
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pubmed:issnType |
Electronic
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
909-11
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pubmed:meshHeading |
pubmed-meshheading:19473366-Adult,
pubmed-meshheading:19473366-Aged,
pubmed-meshheading:19473366-Aged, 80 and over,
pubmed-meshheading:19473366-European Continental Ancestry Group,
pubmed-meshheading:19473366-Female,
pubmed-meshheading:19473366-Gene Frequency,
pubmed-meshheading:19473366-Genetic Predisposition to Disease,
pubmed-meshheading:19473366-Genotype,
pubmed-meshheading:19473366-Humans,
pubmed-meshheading:19473366-Intercellular Signaling Peptides and Proteins,
pubmed-meshheading:19473366-Male,
pubmed-meshheading:19473366-Middle Aged,
pubmed-meshheading:19473366-Parkinson Disease,
pubmed-meshheading:19473366-Poland,
pubmed-meshheading:19473366-Polymorphism, Single Nucleotide,
pubmed-meshheading:19473366-Risk Factors,
pubmed-meshheading:19473366-United States,
pubmed-meshheading:19473366-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
GRN 3'UTR+78 C>T is not associated with risk for Parkinson's disease.
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pubmed:affiliation |
Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA. jasinskamyga.barbara@mayo.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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