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rdf:type |
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lifeskim:mentions |
umls-concept:C0013743,
umls-concept:C0018817,
umls-concept:C0018818,
umls-concept:C0152171,
umls-concept:C0439849,
umls-concept:C0445223,
umls-concept:C0599724,
umls-concept:C0936012,
umls-concept:C1515021,
umls-concept:C1552599,
umls-concept:C1704787
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pubmed:issue |
3
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pubmed:dateCreated |
2010-10-11
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pubmed:abstractText |
Eisenmenger's syndrome (ES) is the most advanced form of pulmonary arterial hypertension related to congenital heart disease. Evolution of pulmonary vascular disease differs markedly between patients with atrial septal defects (ASD) versus ventricular septal defects (VSD), potentially affecting response to treatment. We compared the effects of bosentan and placebo in patients with isolated ASD (ASD subgroup) versus patients with isolated VSD or both defects (VSD subgroup).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1874-1754
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2009 Elsevier Ireland Ltd. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
29
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pubmed:volume |
144
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
373-8
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pubmed:meshHeading |
pubmed-meshheading:19464064-Adult,
pubmed-meshheading:19464064-Antihypertensive Agents,
pubmed-meshheading:19464064-Boston,
pubmed-meshheading:19464064-Canada,
pubmed-meshheading:19464064-Double-Blind Method,
pubmed-meshheading:19464064-Eisenmenger Complex,
pubmed-meshheading:19464064-Exercise,
pubmed-meshheading:19464064-Female,
pubmed-meshheading:19464064-Great Britain,
pubmed-meshheading:19464064-Heart Septal Defects, Atrial,
pubmed-meshheading:19464064-Heart Septal Defects, Ventricular,
pubmed-meshheading:19464064-Hemodynamics,
pubmed-meshheading:19464064-Humans,
pubmed-meshheading:19464064-Hypertension, Pulmonary,
pubmed-meshheading:19464064-Italy,
pubmed-meshheading:19464064-Male,
pubmed-meshheading:19464064-Middle Aged,
pubmed-meshheading:19464064-Netherlands,
pubmed-meshheading:19464064-Ontario,
pubmed-meshheading:19464064-Oximetry,
pubmed-meshheading:19464064-Pulmonary Circulation,
pubmed-meshheading:19464064-Pulmonary Wedge Pressure,
pubmed-meshheading:19464064-Sulfonamides,
pubmed-meshheading:19464064-Switzerland,
pubmed-meshheading:19464064-Treatment Outcome,
pubmed-meshheading:19464064-Vascular Resistance
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pubmed:year |
2010
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pubmed:articleTitle |
Atrial septal defects versus ventricular septal defects in BREATHE-5, a placebo-controlled study of pulmonary arterial hypertension related to Eisenmenger's syndrome: a subgroup analysis.
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pubmed:affiliation |
University Medical Center, University of Groningen, Groningen, The Netherlands. r.m.f.berger@bkk.umcg.nl
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pubmed:publicationType |
Journal Article,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
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