Linked Life Data

19463921

Source:http://linkedlifedata.com/resource/pubmed/id/19463921

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2009-8-31
pubmed:abstractText
Water-soluble polysaccharides were extracted from the fruit pulps of Melia azedarach and some columns were undertaken to isolate the major polysaccharide (MPS-III). Its structural features were elucidated by IR analysis, carbohydrate analysis, periodate oxidation, Smith degradation, methylation analysis and NMR spectroscopy. Then it was evaluated for the cytotoxic activity in vitro against four human cell lines, using the sulphorhodamine B assay. The data obtained indicated that MPS-III contains a alpha(1-->4) main chain backbone composed of arabinose, mannose in a molar ratio of 1.31:1.0 and has alpha(1-->6) branch structure. And MPS-III showed a strong cytotoxic activity in the BGC-823 cell line.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1873-6971
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
80
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
399-403
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Structural features of a new heteropolysaccharide from the fruit bodies of Melia azedarach and its effect on cytotoxic activity.
pubmed:affiliation
Department of Natural Products Chemistry, Institute of Biological Technology, Zhejiang Forestry Academy, 310023 Hangzhou, China. kite006@163.com
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't