Source:http://linkedlifedata.com/resource/pubmed/id/19444577
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
2009-5-15
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| pubmed:abstractText |
We measured the serum concentration of lidocaine after transversus abdominis plane (TAP) block with 40 ml of 1% lidocaine in 12 patients under general anesthesia, using a fluorescence polarization immunoassay. The peak mean serum concentration of lidocaine occurred 30 min after the block (3.6 +/- 0.7 microg x ml(-1)). The highest concentration of lidocaine (5.microg x ml(-1)) was recorded 15 min after the block. These results indicate that a TAP block can potentially cause systemic toxicity of a local anesthetic. The analgesic effect of the TAP block may partially depend on the rise in serum concentration of the local anesthetic.
|
| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
1438-8359
|
| pubmed:author | |
| pubmed:issnType |
Electronic
|
| pubmed:volume |
23
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
298-300
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| pubmed:meshHeading |
pubmed-meshheading:19444577-Abdomen,
pubmed-meshheading:19444577-Adult,
pubmed-meshheading:19444577-Anesthesia, General,
pubmed-meshheading:19444577-Anesthetics, Local,
pubmed-meshheading:19444577-Female,
pubmed-meshheading:19444577-Fluorescence Polarization Immunoassay,
pubmed-meshheading:19444577-Gynecologic Surgical Procedures,
pubmed-meshheading:19444577-Humans,
pubmed-meshheading:19444577-Lidocaine,
pubmed-meshheading:19444577-Middle Aged,
pubmed-meshheading:19444577-Nerve Block,
pubmed-meshheading:19444577-Pain, Postoperative
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| pubmed:year |
2009
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| pubmed:articleTitle |
Serum concentration of lidocaine after transversus abdominis plane block.
|
| pubmed:affiliation |
Department of Anesthesiology, Aichi Gakuin University School of Dentistry, Aichi, Japan.
|
| pubmed:publicationType |
Journal Article
|