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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2009-8-28
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pubmed:abstractText |
Microglia in the central nervous system display a marked structural dynamism in their processes in the resting state. This dynamic behavior, which may play a constitutive surveying role in the uninjured neural parenchyma, is also highly responsive to tissue injury. The role of CX3CR1, a chemokine receptor expressed in microglia, in regulating microglia morphology and dynamic behavior in the resting state and after laser-induced focal injury was examined.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1552-5783
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4444-51
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pubmed:dateRevised |
2011-9-29
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pubmed:meshHeading |
pubmed-meshheading:19443728-Animals,
pubmed-meshheading:19443728-Cell Count,
pubmed-meshheading:19443728-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:19443728-Gene Expression Regulation,
pubmed-meshheading:19443728-Green Fluorescent Proteins,
pubmed-meshheading:19443728-Lasers,
pubmed-meshheading:19443728-Mice,
pubmed-meshheading:19443728-Mice, Inbred C57BL,
pubmed-meshheading:19443728-Mice, Transgenic,
pubmed-meshheading:19443728-Microglia,
pubmed-meshheading:19443728-Microscopy, Confocal,
pubmed-meshheading:19443728-RNA, Messenger,
pubmed-meshheading:19443728-Receptors, Chemokine,
pubmed-meshheading:19443728-Retina,
pubmed-meshheading:19443728-Retinal Neurons,
pubmed-meshheading:19443728-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:19443728-Signal Transduction
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pubmed:year |
2009
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pubmed:articleTitle |
Regulation of dynamic behavior of retinal microglia by CX3CR1 signaling.
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pubmed:affiliation |
Office of the Scientific Director, Division of Epidemiology and Clinical Research, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Intramural
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