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pubmed-article:19439088pubmed:abstractTextThe R952Q variant in the low density lipoprotein receptor-related protein 8 (LRP8)/apolipoprotein E receptor 2 (ApoER2) gene has been recently associated with familial and premature myocardial infarction (MI) by means of genome-wide linkage scan/association studies. We were interested in the possible interaction of the R952Q variant with another established cardiovascular genetic risk factor belonging to the same pathway, namely apolipoprotein E (APOE) epsilon2/epsilon3/epsilon4 genotype, in modulating apolipoprotein E (ApoE) plasma levels and risk of MI.lld:pubmed
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pubmed-article:19439088pubmed:articleTitleAdditive effect of LRP8/APOER2 R952Q variant to APOE epsilon2/epsilon3/epsilon4 genotype in modulating apolipoprotein E concentration and the risk of myocardial infarction: a case-control study.lld:pubmed
pubmed-article:19439088pubmed:affiliationDepartment of Clinical and Experimental Medicine, University of Verona, Verona, Italy. nicola.martinelli@univr.itlld:pubmed
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