pubmed-article:194058 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:194058 | lifeskim:mentions | umls-concept:C0037994 | lld:lifeskim |
pubmed-article:194058 | lifeskim:mentions | umls-concept:C0042776 | lld:lifeskim |
pubmed-article:194058 | lifeskim:mentions | umls-concept:C0521026 | lld:lifeskim |
pubmed-article:194058 | lifeskim:mentions | umls-concept:C0079382 | lld:lifeskim |
pubmed-article:194058 | lifeskim:mentions | umls-concept:C0332307 | lld:lifeskim |
pubmed-article:194058 | lifeskim:mentions | umls-concept:C0025914 | lld:lifeskim |
pubmed-article:194058 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
pubmed-article:194058 | lifeskim:mentions | umls-concept:C0439849 | lld:lifeskim |
pubmed-article:194058 | lifeskim:mentions | umls-concept:C0080194 | lld:lifeskim |
pubmed-article:194058 | lifeskim:mentions | umls-concept:C0162326 | lld:lifeskim |
pubmed-article:194058 | lifeskim:mentions | umls-concept:C0445223 | lld:lifeskim |
pubmed-article:194058 | lifeskim:mentions | umls-concept:C1552599 | lld:lifeskim |
pubmed-article:194058 | lifeskim:mentions | umls-concept:C1704787 | lld:lifeskim |
pubmed-article:194058 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:194058 | pubmed:dateCreated | 1977-7-18 | lld:pubmed |
pubmed-article:194058 | pubmed:abstractText | The genome of the Friend strain of the spleen focus-forming virus (SFFV) has been analyzed by molecular hybridization. SFFV is composed of genetic sequences homologous to Friend type C helper virus (F-MuLV) and SFFV-specific sequences not present in F-MuLV. These SFFV-specific sequences are present in both the Friend and Rauscher strains of murine erythroleukemia virus. The SFFV-specific sequences are partially homologous to three separate strains of mouse xenotropic virus but not to several cloned mouse ecotropic viruses. Thus, the Friend strain of SFFV appears to be a recombinant between a portion of the F-MuLV genome and RNA sequences that are highly related to murine xenotropic viruses. The implications of the acquisition of the xenotropic virus-related sequences are discussed in relation to the leukemogenicity of SFFV, and a model for the pathogenicity of other murine leukemia-inducing viruses is proposed. | lld:pubmed |
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pubmed-article:194058 | pubmed:language | eng | lld:pubmed |
pubmed-article:194058 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:194058 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:194058 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:194058 | pubmed:month | May | lld:pubmed |
pubmed-article:194058 | pubmed:issn | 0022-538X | lld:pubmed |
pubmed-article:194058 | pubmed:author | pubmed-author:ScolnickE MEM | lld:pubmed |
pubmed-article:194058 | pubmed:author | pubmed-author:ParksW PWP | lld:pubmed |
pubmed-article:194058 | pubmed:author | pubmed-author:TroxlerD HDH | lld:pubmed |
pubmed-article:194058 | pubmed:author | pubmed-author:BoyarsJ KJK | lld:pubmed |
pubmed-article:194058 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:194058 | pubmed:volume | 22 | lld:pubmed |
pubmed-article:194058 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:194058 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:194058 | pubmed:pagination | 361-72 | lld:pubmed |
pubmed-article:194058 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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pubmed-article:194058 | pubmed:year | 1977 | lld:pubmed |
pubmed-article:194058 | pubmed:articleTitle | Friend strain of spleen focus-forming virus: a recombinant between mouse type C ecotropic viral sequences and sequences related to xenotropic virus. | lld:pubmed |
pubmed-article:194058 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:194058 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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