Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1977-7-18
pubmed:abstractText
Changes in the dynamic behavior of membrane lipids of mammalian cells induced by adsorption of animal viruses were quantitatively monitored by fluorescence polarization analysis with the aid of the fluorescent probe 1,6-diphenyl 1,3,5-hexatriene embedded in the surface membrane lipid core of intact cells. Adsorption of encephalomyocarditis, West Nile, and polyoma viruses to hamster (baby hamster kidney) and mouse (3T3) cells is accompanied by a rapid and significant increase in the degree of fluidity of membrane lipids of the infected cells. These changes in membrane fluidity, which are virus dose dependent, are inhibited by low temperature and by treatment of the cells before-hand with compounds known to block viral receptors on the cell surface. It is suggested that increase in membrane lipid fluidity, induced by the adsorption of virions, is an early event in the process of cell-virus interactions.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/194057-1059120, http://linkedlifedata.com/resource/pubmed/commentcorrection/194057-1085263, http://linkedlifedata.com/resource/pubmed/commentcorrection/194057-1260056, http://linkedlifedata.com/resource/pubmed/commentcorrection/194057-13491853, http://linkedlifedata.com/resource/pubmed/commentcorrection/194057-13859227, http://linkedlifedata.com/resource/pubmed/commentcorrection/194057-14001211, http://linkedlifedata.com/resource/pubmed/commentcorrection/194057-14240405, http://linkedlifedata.com/resource/pubmed/commentcorrection/194057-14317050, http://linkedlifedata.com/resource/pubmed/commentcorrection/194057-169884, http://linkedlifedata.com/resource/pubmed/commentcorrection/194057-4333397, http://linkedlifedata.com/resource/pubmed/commentcorrection/194057-4335665, http://linkedlifedata.com/resource/pubmed/commentcorrection/194057-4346307, http://linkedlifedata.com/resource/pubmed/commentcorrection/194057-4350966, http://linkedlifedata.com/resource/pubmed/commentcorrection/194057-4351454, http://linkedlifedata.com/resource/pubmed/commentcorrection/194057-4360027, http://linkedlifedata.com/resource/pubmed/commentcorrection/194057-4365361, http://linkedlifedata.com/resource/pubmed/commentcorrection/194057-4371655, http://linkedlifedata.com/resource/pubmed/commentcorrection/194057-4530299, http://linkedlifedata.com/resource/pubmed/commentcorrection/194057-4851371, http://linkedlifedata.com/resource/pubmed/commentcorrection/194057-985887, http://linkedlifedata.com/resource/pubmed/commentcorrection/194057-989043
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0022-538X
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
353-60
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Increase in lipid fluidity of cellular membranes induced by adsorption of RNA and DNA virions.
pubmed:publicationType
Journal Article