rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
2009-4-28
|
pubmed:abstractText |
Morphologically similar cancers display heterogeneous patterns of molecular aberrations and follow substantially different clinical courses. This diversity has become the basis for the definition of molecular phenotypes, with significant implications for therapy. Microarray or proteomic expression profiling is conventionally employed to identify disease-associated genes, however, traditional approaches for the analysis of profiling experiments may miss molecular aberrations which define biologically relevant subtypes.
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
1932-6203
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
4
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
e5337
|
pubmed:dateRevised |
2009-11-18
|
pubmed:meshHeading |
pubmed-meshheading:19399185-Algorithms,
pubmed-meshheading:19399185-Chemotactic Factors,
pubmed-meshheading:19399185-Databases, Genetic,
pubmed-meshheading:19399185-Gene Expression,
pubmed-meshheading:19399185-Gene Expression Profiling,
pubmed-meshheading:19399185-Genetic Markers,
pubmed-meshheading:19399185-Genetic Techniques,
pubmed-meshheading:19399185-Humans,
pubmed-meshheading:19399185-Immunohistochemistry,
pubmed-meshheading:19399185-Neoplasms,
pubmed-meshheading:19399185-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:19399185-Pancreatic Neoplasms,
pubmed-meshheading:19399185-Protein Array Analysis,
pubmed-meshheading:19399185-S100 Proteins,
pubmed-meshheading:19399185-Sensitivity and Specificity,
pubmed-meshheading:19399185-Software
|
pubmed:year |
2009
|
pubmed:articleTitle |
Messina: a novel analysis tool to identify biologically relevant molecules in disease.
|
pubmed:affiliation |
Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Evaluation Studies
|