| pubmed-article:19396160 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19396160 | lifeskim:mentions | umls-concept:C0600148 | lld:lifeskim |
| pubmed-article:19396160 | lifeskim:mentions | umls-concept:C0080194 | lld:lifeskim |
| pubmed-article:19396160 | lifeskim:mentions | umls-concept:C0026882 | lld:lifeskim |
| pubmed-article:19396160 | lifeskim:mentions | umls-concept:C0035681 | lld:lifeskim |
| pubmed-article:19396160 | lifeskim:mentions | umls-concept:C0279516 | lld:lifeskim |
| pubmed-article:19396160 | lifeskim:mentions | umls-concept:C0073313 | lld:lifeskim |
| pubmed-article:19396160 | lifeskim:mentions | umls-concept:C1880355 | lld:lifeskim |
| pubmed-article:19396160 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:19396160 | pubmed:dateCreated | 2009-5-11 | lld:pubmed |
| pubmed-article:19396160 | pubmed:abstractText | We show that selection of drug-resistant bacterial mutants allows the discovery of antibacterial compounds. Mutant strains of a soil-isolated Streptomyces species that does not produce antibacterials synthesize a previously unknown class of antibacterial, which we name piperidamycin. Overall, 6% of non-Streptomyces actinomycetes species and 43% of Streptomyces species that do not produce antibacterials are activated to produce them. The antibacterial-producing mutants all carried mutations in RNA polymerase and/or the ribosomal protein S12. | lld:pubmed |
| pubmed-article:19396160 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19396160 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19396160 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19396160 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19396160 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19396160 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19396160 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19396160 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19396160 | pubmed:month | May | lld:pubmed |
| pubmed-article:19396160 | pubmed:issn | 1546-1696 | lld:pubmed |
| pubmed-article:19396160 | pubmed:author | pubmed-author:OchiKozoK | lld:pubmed |
| pubmed-article:19396160 | pubmed:author | pubmed-author:YoshidaMitsur... | lld:pubmed |
| pubmed-article:19396160 | pubmed:author | pubmed-author:Ohnishi-Kamey... | lld:pubmed |
| pubmed-article:19396160 | pubmed:author | pubmed-author:HosakaTakeshi... | lld:pubmed |
| pubmed-article:19396160 | pubmed:author | pubmed-author:TsurumiYasuhi... | lld:pubmed |
| pubmed-article:19396160 | pubmed:author | pubmed-author:KodaniShinyaS | lld:pubmed |
| pubmed-article:19396160 | pubmed:author | pubmed-author:FujieAkihikoA | lld:pubmed |
| pubmed-article:19396160 | pubmed:author | pubmed-author:MurakamiKanaK | lld:pubmed |
| pubmed-article:19396160 | pubmed:author | pubmed-author:MuramatsuHide... | lld:pubmed |
| pubmed-article:19396160 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19396160 | pubmed:volume | 27 | lld:pubmed |
| pubmed-article:19396160 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19396160 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19396160 | pubmed:pagination | 462-4 | lld:pubmed |
| pubmed-article:19396160 | pubmed:meshHeading | pubmed-meshheading:19396160... | lld:pubmed |
| pubmed-article:19396160 | pubmed:meshHeading | pubmed-meshheading:19396160... | lld:pubmed |
| pubmed-article:19396160 | pubmed:meshHeading | pubmed-meshheading:19396160... | lld:pubmed |
| pubmed-article:19396160 | pubmed:meshHeading | pubmed-meshheading:19396160... | lld:pubmed |
| pubmed-article:19396160 | pubmed:meshHeading | pubmed-meshheading:19396160... | lld:pubmed |
| pubmed-article:19396160 | pubmed:meshHeading | pubmed-meshheading:19396160... | lld:pubmed |
| pubmed-article:19396160 | pubmed:meshHeading | pubmed-meshheading:19396160... | lld:pubmed |
| pubmed-article:19396160 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:19396160 | pubmed:articleTitle | Antibacterial discovery in actinomycetes strains with mutations in RNA polymerase or ribosomal protein S12. | lld:pubmed |
| pubmed-article:19396160 | pubmed:affiliation | National Food Research Institute, Tsukuba, Ibaraki, Japan. | lld:pubmed |
| pubmed-article:19396160 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19396160 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:19396160 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:19396160 | lld:pubmed |
