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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2009-9-23
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pubmed:abstractText |
Allergic disorders are characterized by an increase in the Th2 cytokines IL-4, IL-5 and IL-13, produced primarily by Th2 cells. These cells are marked by the expression of CRTh2 (chemoattractant receptor-homologous molecule expressed on Th2 cells), a receptor for prostaglandin D(2). As genetic variation plays a significant role in the predisposition for allergic disorders, we investigated the influence of single nucleotide polymorphisms (SNPs) in CRTh2.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1398-9995
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1478-85
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pubmed:meshHeading |
pubmed-meshheading:19392992-Asthma,
pubmed-meshheading:19392992-Child,
pubmed-meshheading:19392992-Cross-Sectional Studies,
pubmed-meshheading:19392992-Eczema,
pubmed-meshheading:19392992-Food Hypersensitivity,
pubmed-meshheading:19392992-Genetic Variation,
pubmed-meshheading:19392992-Genotype,
pubmed-meshheading:19392992-Germany,
pubmed-meshheading:19392992-Humans,
pubmed-meshheading:19392992-Hypersensitivity, Immediate,
pubmed-meshheading:19392992-Phenotype,
pubmed-meshheading:19392992-Polymorphism, Single Nucleotide,
pubmed-meshheading:19392992-Receptors, Immunologic,
pubmed-meshheading:19392992-Receptors, Prostaglandin,
pubmed-meshheading:19392992-Respiratory Sounds,
pubmed-meshheading:19392992-Rhinitis, Allergic, Seasonal
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pubmed:year |
2009
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pubmed:articleTitle |
Genetic variation in CRTh2 influences development of allergic phenotypes.
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pubmed:affiliation |
Department of Medicine, Pulmonary Research Group, University of Alberta, Edmonton, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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