|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1
|
|
pubmed:dateCreated |
2009-6-15
|
|
pubmed:abstractText |
Reduced excitability and gap junction expression are commonly found in electrically remodelled diseased hearts, but their contribution to slow conduction and arrhythmias is unclear. In this study, we have investigated the effect of isolated and combined reductions in membrane excitability and intercellular coupling on impulse propagation and arrhythmogeneity in genetically modified mice.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
1755-3245
|
|
pubmed:author |
pubmed-author:BezzinaConnie RCR,
pubmed-author:BoulaksilMohamedM,
pubmed-author:HauerRichard N WRN,
pubmed-author:NoormanMaartjeM,
pubmed-author:RemmeCarol AnnCA,
pubmed-author:SteinMèraM,
pubmed-author:de BakkerJacques M TJM,
pubmed-author:van RijenHarold V MHV,
pubmed-author:van StuijvenbergLeonieL,
pubmed-author:van VeenToon A BTA,
pubmed-author:van der NagelRoelR
|
|
pubmed:issnType |
Electronic
|
|
pubmed:day |
1
|
|
pubmed:volume |
83
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
52-60
|
|
pubmed:dateRevised |
2011-7-22
|
|
pubmed:meshHeading |
pubmed-meshheading:19389723-Animals,
pubmed-meshheading:19389723-Arrhythmias, Cardiac,
pubmed-meshheading:19389723-Cell Membrane,
pubmed-meshheading:19389723-Connexin 43,
pubmed-meshheading:19389723-Disease Models, Animal,
pubmed-meshheading:19389723-Electrocardiography,
pubmed-meshheading:19389723-Electrophysiologic Techniques, Cardiac,
pubmed-meshheading:19389723-Female,
pubmed-meshheading:19389723-Heart Conduction System,
pubmed-meshheading:19389723-Heart Ventricles,
pubmed-meshheading:19389723-Intercellular Junctions,
pubmed-meshheading:19389723-Male,
pubmed-meshheading:19389723-Mice,
pubmed-meshheading:19389723-Mice, Transgenic,
pubmed-meshheading:19389723-Sodium Channels
|
|
pubmed:year |
2009
|
|
pubmed:articleTitle |
Combined reduction of intercellular coupling and membrane excitability differentially affects transverse and longitudinal cardiac conduction.
|
|
pubmed:affiliation |
Division of Heart and Lungs, Department of Medical Physiology, University Medical Center Utrecht, Yalelaan 50, Utrecht, The Netherlands.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
