Source:http://linkedlifedata.com/resource/pubmed/id/19387683
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2009-4-30
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pubmed:abstractText |
Focal nodular hyperplasia (FNH) of the liver is considered to develop as a hyperplastic response to a preexisting vascular abnormality. From the pathogenic point of view, we studied histological alterations in the extranodular background liver tissue of FNH (FNH-bg-liver). We compared ten FNH-bg-livers with ten non-FNH cases (non-FNH-liver) and found small uniform nodule formations with ring-like siderosis in the FNH-bg-livers (4/7, 57%) but not in the non-FNH-livers. Abnormal small arteries not accompanied by portal tracts were observed in six of six FNH-bg-livers for which immunohistochemical study was available, while this was observed in only three of the ten non-FNH-livers. CD34-positive sinusoids around the portal tracts were observed in only the FNH-bg-livers (3/6, 50%). Further, two of ten FNH-bg-livers had ectopic pancreatic tissue. Ring-like siderosis, abnormal small arteries, CD34-positive sinusoids, and ectopic pancreatic tissue were characteristic in the extranodular background liver tissue in cases of FNH.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0945-6317
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pubmed:author |
pubmed-author:BanShinichiS,
pubmed-author:MotosugiUtarohU,
pubmed-author:MurataShin-IchiS,
pubmed-author:NagataKohjiK,
pubmed-author:SakuraiTakakiT,
pubmed-author:SannoheSeiyaS,
pubmed-author:ShimizuMichioM,
pubmed-author:ShimizuYoshihikoY,
pubmed-author:YamaguchiHiroshiH,
pubmed-author:YasudaMasanoriM
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pubmed:issnType |
Print
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pubmed:volume |
454
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
557-62
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pubmed:meshHeading |
pubmed-meshheading:19387683-Adult,
pubmed-meshheading:19387683-Arteries,
pubmed-meshheading:19387683-Biological Markers,
pubmed-meshheading:19387683-Choristoma,
pubmed-meshheading:19387683-Female,
pubmed-meshheading:19387683-Focal Nodular Hyperplasia,
pubmed-meshheading:19387683-Hepatectomy,
pubmed-meshheading:19387683-Humans,
pubmed-meshheading:19387683-Immunohistochemistry,
pubmed-meshheading:19387683-Liver,
pubmed-meshheading:19387683-Liver Diseases,
pubmed-meshheading:19387683-Male,
pubmed-meshheading:19387683-Middle Aged,
pubmed-meshheading:19387683-Pancreas,
pubmed-meshheading:19387683-Siderosis
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pubmed:year |
2009
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pubmed:articleTitle |
Extranodular background liver parenchyma of focal nodular hyperplasia: histopathological characteristics.
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pubmed:affiliation |
Department of Pathology, Saitama Medical University International Medical Center, 1397-1 Yamane, Hidaka-shi, Saitama-ken, 350-1298, Japan.
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pubmed:publicationType |
Journal Article
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