Source:http://linkedlifedata.com/resource/pubmed/id/19378139
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2009-4-20
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pubmed:abstractText |
Multiple alignment of DNA sequences is an important step in various molecular biological analyses. As a large amount of sequence data is becoming available through genome and other large-scale sequencing projects, scalability, as well as accuracy, is currently required for a multiple sequence alignment (MSA) program. In this chapter, we outline the algorithms of an MSA program MAFFT and provide practical advice, focusing on several typical situations a biologist sometimes faces. For genome alignment, which is beyond the scope of MAFFT, we introduce two tools: TBA and MAUVE.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
1064-3745
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
537
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
39-64
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pubmed:meshHeading |
pubmed-meshheading:19378139-Algorithms,
pubmed-meshheading:19378139-Animals,
pubmed-meshheading:19378139-Base Sequence,
pubmed-meshheading:19378139-Computational Biology,
pubmed-meshheading:19378139-Humans,
pubmed-meshheading:19378139-Molecular Sequence Data,
pubmed-meshheading:19378139-Sequence Alignment,
pubmed-meshheading:19378139-Sequence Analysis, DNA,
pubmed-meshheading:19378139-Software
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pubmed:year |
2009
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pubmed:articleTitle |
Multiple alignment of DNA sequences with MAFFT.
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pubmed:affiliation |
Digital Medicine Initiative, Kyushu University, Fukuoka, Japan.
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pubmed:publicationType |
Journal Article
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