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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2009-6-30
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pubmed:abstractText |
Early metastasis is a hallmark of pancreatic ductal adenocarcinoma and responsible for >90% of pancreatic cancer death. Because little is known about the biology and genetics of the metastatic process, we desired to elucidate molecular pathways mediating pancreatic cancer metastasis in vivo by an unbiased forward genetic approach.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/CDH1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Cadherins,
http://linkedlifedata.com/resource/pubmed/chemical/Hdac1 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Hdac2 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Histone Deacetylase 1,
http://linkedlifedata.com/resource/pubmed/chemical/Histone Deacetylase 2,
http://linkedlifedata.com/resource/pubmed/chemical/Histone Deacetylase Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Histone Deacetylases,
http://linkedlifedata.com/resource/pubmed/chemical/Hydroxamic Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Repressor Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/snail family transcription factors,
http://linkedlifedata.com/resource/pubmed/chemical/trichostatin A
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1528-0012
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pubmed:author |
pubmed-author:BrandlMartinaM,
pubmed-author:EserStefanS,
pubmed-author:MagesJörgJ,
pubmed-author:MesserMarlenaM,
pubmed-author:PagelPhilippP,
pubmed-author:PaulMariel CMC,
pubmed-author:SaurDieterD,
pubmed-author:SchmidRoland MRM,
pubmed-author:SchmidtAnnegretA,
pubmed-author:SchneiderGünterG,
pubmed-author:SchniekeAngelikaA,
pubmed-author:SeidlerBarbaraB,
pubmed-author:von BurstinJohannesJ,
pubmed-author:von WerderAlexanderA
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pubmed:issnType |
Electronic
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pubmed:volume |
137
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
361-71, 371.e1-5
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:19362090-Animals,
pubmed-meshheading:19362090-Antineoplastic Agents,
pubmed-meshheading:19362090-Cadherins,
pubmed-meshheading:19362090-Cell Line, Tumor,
pubmed-meshheading:19362090-Cell Transdifferentiation,
pubmed-meshheading:19362090-Gene Expression Profiling,
pubmed-meshheading:19362090-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:19362090-Gene Silencing,
pubmed-meshheading:19362090-Histone Deacetylase 1,
pubmed-meshheading:19362090-Histone Deacetylase 2,
pubmed-meshheading:19362090-Histone Deacetylase Inhibitors,
pubmed-meshheading:19362090-Histone Deacetylases,
pubmed-meshheading:19362090-Humans,
pubmed-meshheading:19362090-Hydroxamic Acids,
pubmed-meshheading:19362090-Lung Neoplasms,
pubmed-meshheading:19362090-Mice,
pubmed-meshheading:19362090-Mice, Nude,
pubmed-meshheading:19362090-Pancreatic Neoplasms,
pubmed-meshheading:19362090-Promoter Regions, Genetic,
pubmed-meshheading:19362090-RNA Interference,
pubmed-meshheading:19362090-Repressor Proteins,
pubmed-meshheading:19362090-Transcription Factors,
pubmed-meshheading:19362090-Transfection
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pubmed:year |
2009
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pubmed:articleTitle |
E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/HDAC2 repressor complex.
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pubmed:affiliation |
II. Medizinische Klinik, Technische Universität München, Munich, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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