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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2009-4-9
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pubmed:abstractText |
CYP3A isoforms account for about 30% of total hepatic P450s. Most statins have been accepted probes for CYP3A4. The metabolic ratio of atorvastatin/ortho-hydroxyatorvastatin showed a bimodal distribution with respect to metabolism of atorvastatin. These observations showed that the frequency of occurrence of the poor metabolizer phenotype is 2.4 % in the Gujarat subjects.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1872-3128
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
5-10
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pubmed:meshHeading |
pubmed-meshheading:19356063-Adult,
pubmed-meshheading:19356063-Cytochrome P-450 CYP3A,
pubmed-meshheading:19356063-Female,
pubmed-meshheading:19356063-Gene Frequency,
pubmed-meshheading:19356063-Heptanoic Acids,
pubmed-meshheading:19356063-Humans,
pubmed-meshheading:19356063-Hydroxymethylglutaryl-CoA Reductase Inhibitors,
pubmed-meshheading:19356063-India,
pubmed-meshheading:19356063-Isoenzymes,
pubmed-meshheading:19356063-Male,
pubmed-meshheading:19356063-Phenotype,
pubmed-meshheading:19356063-Polymorphism, Genetic,
pubmed-meshheading:19356063-Pyrroles,
pubmed-meshheading:19356063-Young Adult
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pubmed:year |
2008
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pubmed:articleTitle |
Phenotyping of cytochrome P450 3A enzyme in Gujarat population.
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pubmed:affiliation |
K. B. Institute of Pharmaceutical Education and Research. Sector 23, Gandhinagar, Gujarat -382023, India. janiashutosh@gmail.com
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pubmed:publicationType |
Journal Article,
Clinical Trial
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