rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2009-8-26
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pubmed:abstractText |
From the standpoint of normal embryologic development, the palpebral fissures are generally considered to be determined by and dependent on the underlying optic vesicles, outpouchings of the frontal area of the developing fetal brain. It has been suggested that short palpebral fissures are a reflection of an underlying defect in specific areas of forebrain development. Alternatively, short palpebral fissures, seen in a number of multiple malformation syndromes associated with small occipitofrontal circumference (OFC), such as the fetal alcohol syndrome (FAS), might be proportionally small as a reflection of the microcephaly. The purpose of this study was to examine whether short palpebral fissures are independent of or determined by the OFC.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1542-0760
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
85
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
695-9
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pubmed:dateRevised |
2011-9-26
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pubmed:meshHeading |
pubmed-meshheading:19350654-Adolescent,
pubmed-meshheading:19350654-Cephalometry,
pubmed-meshheading:19350654-Child,
pubmed-meshheading:19350654-Child, Preschool,
pubmed-meshheading:19350654-Craniofacial Abnormalities,
pubmed-meshheading:19350654-Female,
pubmed-meshheading:19350654-Fetal Alcohol Syndrome,
pubmed-meshheading:19350654-Frontal Lobe,
pubmed-meshheading:19350654-Humans,
pubmed-meshheading:19350654-Infant,
pubmed-meshheading:19350654-Male,
pubmed-meshheading:19350654-Microcephaly,
pubmed-meshheading:19350654-Pregnancy,
pubmed-meshheading:19350654-Prenatal Exposure Delayed Effects,
pubmed-meshheading:19350654-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
Developmental pathogenesis of short palpebral fissure length in children with fetal alcohol syndrome.
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pubmed:affiliation |
Department of Pediatrics, University of California, San Diego, La Jolla, California 92093-0828, USA. klyons@ucsd.edu
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pubmed:publicationType |
Journal Article,
Evaluation Studies,
Research Support, N.I.H., Extramural
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