Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1991-12-26
pubmed:abstractText
Many principles that originate in the operating room and in fluid mechanics modeling are relevant to endotracheal intubation in the pulmonary and critical care setting. These factors should be appreciated by pulmonologists and intensivists, as they may contribute to improved safety during the process of airway access. The usual reflex responses to stimulation of oropharyngeal and upper airway receptors include glottic closure, hypertension, tachycardia, and reflex bronchoconstriction. These reflexes can be modified by technical or pharmacologic reduction of sensory receptor stimulation or by parenteral agents, which diminish efferent responses, including anesthetics, vasoactive drugs, and adrenergic blockers. Topical anesthesia and parenteral sedatives may be the preferred agents when overall risk and benefit are considered. Intubation also has consequences related to a reduction in airway caliber, to changes in respiratory mechanics, and to the creation of turbulent airflow in the endotracheal tube.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0272-5231
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
425-32
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Physiologic consequences of tracheal intubation.
pubmed:affiliation
Respiratory and Critical Care Division, Washington University School of Medicine, St. Louis, Missouri.
pubmed:publicationType
Journal Article, Review