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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2009-9-8
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pubmed:abstractText |
Pulmonary artery remodeling triggered by alveolar hypoxia is considered the main mechanism of pulmonary hypertension (PH) in COPD patients. We hypothesized that the risk for PH in COPD is increased by an elevation in the proinflammatory cytokines interleukin (IL)-6, monocyte chemoattractant protein-1 (MCP-1), and IL-1beta, as well as by specific genetic polymorphisms of these cytokines.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1931-3543
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pubmed:author |
pubmed-author:AdnotSergeS,
pubmed-author:BrandtChristianC,
pubmed-author:CanuetMatthieuM,
pubmed-author:ChaouatAriA,
pubmed-author:ChouaidChristosC,
pubmed-author:EddahibiSaadiaS,
pubmed-author:HesJ PJP,
pubmed-author:HoussetBrunoB,
pubmed-author:Le CorvoisierPhilippeP,
pubmed-author:MaitreBernardB,
pubmed-author:SavaleLaurentL,
pubmed-author:SztrymfBenjaminB,
pubmed-author:WeitzenblumEmmanuelE
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pubmed:issnType |
Electronic
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pubmed:volume |
136
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
678-87
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pubmed:dateRevised |
2010-5-5
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pubmed:meshHeading |
pubmed-meshheading:19349390-Adult,
pubmed-meshheading:19349390-Aged,
pubmed-meshheading:19349390-Case-Control Studies,
pubmed-meshheading:19349390-Chemokine CCL2,
pubmed-meshheading:19349390-Chi-Square Distribution,
pubmed-meshheading:19349390-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:19349390-Female,
pubmed-meshheading:19349390-Gene Expression,
pubmed-meshheading:19349390-Genotype,
pubmed-meshheading:19349390-Humans,
pubmed-meshheading:19349390-Hypertension, Pulmonary,
pubmed-meshheading:19349390-Interleukin-1beta,
pubmed-meshheading:19349390-Interleukin-6,
pubmed-meshheading:19349390-Male,
pubmed-meshheading:19349390-Middle Aged,
pubmed-meshheading:19349390-Polymorphism, Genetic,
pubmed-meshheading:19349390-Pulmonary Disease, Chronic Obstructive,
pubmed-meshheading:19349390-Regression Analysis,
pubmed-meshheading:19349390-Respiratory Function Tests,
pubmed-meshheading:19349390-Statistics, Nonparametric
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pubmed:year |
2009
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pubmed:articleTitle |
Role for interleukin-6 in COPD-related pulmonary hypertension.
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pubmed:affiliation |
Service des Maladies Respiratoires et Réanimation Respiratoire, Centre Hospitalier Régional Universitaire de Nancy, Hôpital d'adultes de Brabois, Allée du Morvan, 54511 Vandoeuvre-lès-Nancy Cedex, France. a.chaouat@chu-nancy.fr
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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