Source:http://linkedlifedata.com/resource/pubmed/id/19348791
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2009-7-6
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pubmed:abstractText |
Hydatidiform moles are gestational trophoblastic neoplasms that include both partial and complete moles. Apoptosis plays important roles in the normal placental morphogenesis and in the pathogenesis of the gestational trophoblastic neoplasia. TP53 is a tumor suppressor gene (pro-apoptotic molecule) that maintains genomic stability either by inducing cell-cycle arrest or apoptosis. BCL-2 is a proto-oncogene (a pro-survival molecule) that enhances growth and survival of cells. Epidermal growth factor receptor (EGF-R) is a transmembrane glycoprotein, which can bind and be activated by various ligands. It stimulates cell division and differentiation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1096-0945
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
87
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
63-9
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:19348791-Female,
pubmed-meshheading:19348791-Humans,
pubmed-meshheading:19348791-Hydatidiform Mole,
pubmed-meshheading:19348791-Morphogenesis,
pubmed-meshheading:19348791-Placenta,
pubmed-meshheading:19348791-Pregnancy,
pubmed-meshheading:19348791-Pregnancy Trimester, First,
pubmed-meshheading:19348791-Proto-Oncogene Proteins c-bcl-2,
pubmed-meshheading:19348791-Receptor, Epidermal Growth Factor,
pubmed-meshheading:19348791-Tumor Suppressor Protein p53,
pubmed-meshheading:19348791-Uterine Neoplasms
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pubmed:year |
2009
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pubmed:articleTitle |
Analysis of p53, BCL-2 and epidermal growth factor receptor protein expression in the partial and complete hydatidiform moles.
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pubmed:affiliation |
Department of Pathology, Faculty of Medicine, Assuit University, Assuit, Egypt. mrcpath17@gmail.com
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pubmed:publicationType |
Journal Article
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