Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2009-7-6
pubmed:abstractText
Hydatidiform moles are gestational trophoblastic neoplasms that include both partial and complete moles. Apoptosis plays important roles in the normal placental morphogenesis and in the pathogenesis of the gestational trophoblastic neoplasia. TP53 is a tumor suppressor gene (pro-apoptotic molecule) that maintains genomic stability either by inducing cell-cycle arrest or apoptosis. BCL-2 is a proto-oncogene (a pro-survival molecule) that enhances growth and survival of cells. Epidermal growth factor receptor (EGF-R) is a transmembrane glycoprotein, which can bind and be activated by various ligands. It stimulates cell division and differentiation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1096-0945
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
87
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
63-9
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Analysis of p53, BCL-2 and epidermal growth factor receptor protein expression in the partial and complete hydatidiform moles.
pubmed:affiliation
Department of Pathology, Faculty of Medicine, Assuit University, Assuit, Egypt. mrcpath17@gmail.com
pubmed:publicationType
Journal Article