rdf:type |
|
lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0030274,
umls-concept:C0079419,
umls-concept:C0185117,
umls-concept:C0387583,
umls-concept:C0543467,
umls-concept:C0812222,
umls-concept:C1134719,
umls-concept:C1514888,
umls-concept:C1707520,
umls-concept:C2911684
|
pubmed:issue |
5
|
pubmed:dateCreated |
2009-6-24
|
pubmed:abstractText |
Cyclooxygenase-2 (COX-2) and p53 represent molecules linked to oncogenesis of pancreatic cancer, and there is also a known regulatory loop between mouse double minute 2 (MDM2) and p53. The complex cross talks between p53 and COX-2 and scenarios explaining patterns of p53 and COX-2 expressions in precursor and cancer lesions have been recently reported.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
1536-4828
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
38
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
565-71
|
pubmed:dateRevised |
2010-11-18
|
pubmed:meshHeading |
pubmed-meshheading:19346994-Adult,
pubmed-meshheading:19346994-Aged,
pubmed-meshheading:19346994-Aged, 80 and over,
pubmed-meshheading:19346994-Carcinoma, Pancreatic Ductal,
pubmed-meshheading:19346994-Cyclooxygenase 2,
pubmed-meshheading:19346994-Female,
pubmed-meshheading:19346994-Humans,
pubmed-meshheading:19346994-Immunohistochemistry,
pubmed-meshheading:19346994-Kaplan-Meier Estimate,
pubmed-meshheading:19346994-Male,
pubmed-meshheading:19346994-Middle Aged,
pubmed-meshheading:19346994-Pancreatectomy,
pubmed-meshheading:19346994-Pancreatic Neoplasms,
pubmed-meshheading:19346994-Proportional Hazards Models,
pubmed-meshheading:19346994-Proto-Oncogene Proteins c-mdm2,
pubmed-meshheading:19346994-Tumor Suppressor Protein p53
|
pubmed:year |
2009
|
pubmed:articleTitle |
Clinicopathological correlations of cyclooxygenase-2, MDM2, and p53 expressions in surgically resectable pancreatic invasive ductal adenocarcinoma.
|
pubmed:affiliation |
Department of Pathology, Medical Faculty of Masaryk University, St. Anne's University Hospital, Brno, Czech Republic. marketa.hermanova@fnusa.cz
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|