19334791

Source:http://linkedlifedata.com/resource/pubmed/id/19334791

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0454169, umls-concept:C0870071, umls-concept:C1553035
pubmed:issue	2
pubmed:dateCreated	2009-4-1
pubmed:abstractText	The purpose of this study was to commission a first-of-its-kind dual-layer micro multileaf collimator (mMLC) system by using Monte Carlo dose calculations. The mMLC is attached on a Varian 600C linac. Having a lower and an upper layer of MLC leaves, this mMLC allows for field shaping in two orthogonal directions. The commissioning of the system was performed in two steps: without and with the mMLC attached on the linac. The treatment head without and with the mMLC was modeled in the BEAMnrc Monte Carlo (MC) code. The scoring planes for the phase space files were specified below the linac's secondary collimators (jaws) and above and below the mMLC. With the mMLC attached to the linac the field size was defined by the jaws as 10 x 10 cm(2), which is also the maximum possible field size that can be shaped by the mMLC. For the commissioning of the linac, several fields of various sizes were simulated and compared against ionization chamber measurements in a water phantom. Output factors for several field sizes, as well as percent depth dose curves and dose profiles for rectangular and irregular shape fields, were calculated and compared against measurements in water. Agreement between measured and calculated data was better than 1% and less than 1.0 mm in the penumbra region for open fields. With the mMLC attached, the agreement between measurements and MC calculations is within 1.0% or 1.0 mm in the penumbra region.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/101140941
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:month	Apr
pubmed:issn	1533-0346
pubmed:author	pubmed-author:GiantsoudiDD, pubmed-author:LieII, pubmed-author:PapanikolaouNN, pubmed-author:SheGG, pubmed-author:StathakisSS
pubmed:issnType	Print
pubmed:volume	8
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	105-14
pubmed:meshHeading	pubmed-meshheading:19334791-Computer Simulation, pubmed-meshheading:19334791-Monte Carlo Method, pubmed-meshheading:19334791-Radiotherapy, Conformal, pubmed-meshheading:19334791-Radiotherapy Dosage
pubmed:year	2009
pubmed:articleTitle	Monte Carlo Modeling and Commissioning of a Dual-layer Micro Multileaf Collimator.
pubmed:affiliation	Cancer Therapy and Research Center at Univ of Texas Health Science Center, 7979 Wurzbach Rd., San Antonio, TX 78229, USA.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't