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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2009-2-20
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pubmed:abstractText |
Clinical deterioration on drug therapy for tuberculosis is a common cause of hospital admission in Africa. Potential causes for clinical deterioration in settings of high HIV-1 prevalence include drug resistant Mycobacterium tuberculosis (M.tb), co-morbid illnesses, poor adherence to therapy, tuberculosis associated-immune reconstitution inflammatory syndrome (TB-IRIS) and subtherapeutic antitubercular drug levels. It is important to derive a rapid diagnostic work-up to determine the cause of clinical deterioration as well as specific management to prevent further clinical deterioration and death. We undertook this study among tuberculosis (TB) patients referred to an adult district level hospital situated in a high HIV-1 prevalence setting to determine the frequency, reasons and outcome for such clinical deterioration.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19229341-10998389,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19229341-11579270,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19229341-11598835,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19229341-11931402,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19229341-12416451,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19229341-15578375,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19229341-15609223,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19229341-15786886,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19229341-15919622,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19229341-17068648,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19229341-17545706,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19229341-17624828,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19229341-17719083,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19229341-17993418,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19229341-18197725,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19229341-18652998,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19229341-19011397,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19229341-2569610,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19229341-8096066,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19229341-8561978,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19229341-9655723
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1932-6203
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e4520
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pubmed:dateRevised |
2011-6-20
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pubmed:meshHeading |
pubmed-meshheading:19229341-AIDS-Related Opportunistic Infections,
pubmed-meshheading:19229341-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:19229341-Adolescent,
pubmed-meshheading:19229341-Adult,
pubmed-meshheading:19229341-Antitubercular Agents,
pubmed-meshheading:19229341-Female,
pubmed-meshheading:19229341-HIV-1,
pubmed-meshheading:19229341-Hospitals, District,
pubmed-meshheading:19229341-Humans,
pubmed-meshheading:19229341-Male,
pubmed-meshheading:19229341-Middle Aged,
pubmed-meshheading:19229341-Prospective Studies,
pubmed-meshheading:19229341-South Africa,
pubmed-meshheading:19229341-Treatment Failure,
pubmed-meshheading:19229341-Tuberculosis,
pubmed-meshheading:19229341-Tuberculosis, Multidrug-Resistant,
pubmed-meshheading:19229341-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
Clinical deterioration during antitubercular treatment at a district hospital in South Africa: the importance of drug resistance and AIDS defining illnesses.
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pubmed:affiliation |
Department of Medicine, University of Cape Town, Cape Town, South Africa. dominiquepepper@gmail.com
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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