Linked Life Data

19228042

Source:http://linkedlifedata.com/resource/pubmed/id/19228042

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2009-3-13
pubmed:abstractText
The first total synthesis of ipomoeassin F was carried out using a convergent approach that relied upon the use of Schmidt glycosidation technology for the coupling of two suitably protected monosaccharide fragments. After two steps, ring-closing metathesis was used to form the macrocyclic ring, and seven more steps then furnished ipomoeassin F. In vitro inhibitory activity against a four-panel cell line showed low nanomolar inhibitory activity.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1523-7052
pubmed:author
pubmed:issnType
Electronic
pubmed:day
19
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1417-20
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Total synthesis of ipomoeassin F.
pubmed:affiliation
Department of Discovery Chemistry, Eisai Research Institute, 4 Corporate Drive, Andover, Massachusetts 01810, USA. maarten_postema@eri.eisai.com
pubmed:publicationType
Journal Article