Cigarette smoking in asthma patients causes insensitivity to inhaled glucocorticoids (GCs). We tested the hypothesis that smoking causes GC insensitivity in alveolar macrophages (AMs) obtained from patients with asthma.
Medicines Evaluation Unit, School of Translational Medicine, University of Manchester, Wythenshawe Hospital, Manchester M23 9QZ, UK. binitakane@yahoo.com