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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2009-3-2
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pubmed:abstractText |
Vitamin E analogues are potent novel anticancer drugs. The purpose of this study was to elucidate the cellular target by which these agents, represented by alpha-tocopoheryl succinate (alpha-TOS), suppress tumors in vivo, with the focus on the mitochondrial complex II (CII).
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antioxidants,
http://linkedlifedata.com/resource/pubmed/chemical/Electron Transport Complex II,
http://linkedlifedata.com/resource/pubmed/chemical/Green Fluorescent Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Reactive Oxygen Species,
http://linkedlifedata.com/resource/pubmed/chemical/SDHC protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/alpha-Tocopherol,
http://linkedlifedata.com/resource/pubmed/chemical/enhanced green fluorescent protein,
http://linkedlifedata.com/resource/pubmed/chemical/respiratory complex II
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1078-0432
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pubmed:author |
pubmed-author:BrunkUlf TUT,
pubmed-author:ButcherBevanB,
pubmed-author:DongLan-FengLF,
pubmed-author:FreemanRuthR,
pubmed-author:GoodwinJacobJ,
pubmed-author:KONMM,
pubmed-author:Marin-HernandezAlvaroA,
pubmed-author:Moreno-SanchezRafaelR,
pubmed-author:NeuzilJiriJ,
pubmed-author:RalphStephen JSJ,
pubmed-author:Rodriguez-EnriquezSaraS,
pubmed-author:RohlenaJakubJ,
pubmed-author:SchefflerImmo EIE,
pubmed-author:StanticMarinaM,
pubmed-author:ValisKarelK,
pubmed-author:WittingPaul KPK,
pubmed-author:ZobalovaRenataR
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1593-600
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pubmed:dateRevised |
2011-4-28
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pubmed:meshHeading |
pubmed-meshheading:19223492-Animals,
pubmed-meshheading:19223492-Antioxidants,
pubmed-meshheading:19223492-Apoptosis,
pubmed-meshheading:19223492-Blotting, Western,
pubmed-meshheading:19223492-Cell Transformation, Neoplastic,
pubmed-meshheading:19223492-Cells, Cultured,
pubmed-meshheading:19223492-Colony-Forming Units Assay,
pubmed-meshheading:19223492-Cricetinae,
pubmed-meshheading:19223492-Cricetulus,
pubmed-meshheading:19223492-Electron Transport Complex II,
pubmed-meshheading:19223492-Fibroblasts,
pubmed-meshheading:19223492-Green Fluorescent Proteins,
pubmed-meshheading:19223492-Lung,
pubmed-meshheading:19223492-Lung Neoplasms,
pubmed-meshheading:19223492-Membrane Proteins,
pubmed-meshheading:19223492-Mice,
pubmed-meshheading:19223492-Mice, Inbred BALB C,
pubmed-meshheading:19223492-Mice, Nude,
pubmed-meshheading:19223492-Mitochondria,
pubmed-meshheading:19223492-Oxygen Consumption,
pubmed-meshheading:19223492-RNA, Messenger,
pubmed-meshheading:19223492-Reactive Oxygen Species,
pubmed-meshheading:19223492-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:19223492-alpha-Tocopherol
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pubmed:year |
2009
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pubmed:articleTitle |
Suppression of tumor growth in vivo by the mitocan alpha-tocopheryl succinate requires respiratory complex II.
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pubmed:affiliation |
Apoptosis Research Group and Genomic Research Centre, School of Medical Science, Griffith University, Southport, Queensland, Australia. l.dong@griffith.edu.au
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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