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rdf:type |
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lifeskim:mentions |
umls-concept:C0005682,
umls-concept:C0017262,
umls-concept:C0035696,
umls-concept:C0185117,
umls-concept:C0227598,
umls-concept:C0389995,
umls-concept:C1135183,
umls-concept:C1140999,
umls-concept:C1267092,
umls-concept:C1280500,
umls-concept:C1879547,
umls-concept:C1999216,
umls-concept:C2911684
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pubmed:issue |
6
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pubmed:dateCreated |
2009-7-15
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pubmed:abstractText |
To investigate the concentration and activity of RhoA in detrusor and urothelium, as well as the effects of a Rho-kinase inhibitor, Y-27632 [(+)-(R)-trans-4-(1-aminoethyl)-N-(4-pyridyl) cyclohexanecarboxamide dihydrochloride], on contraction of the pig urinary bladder.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Amides,
http://linkedlifedata.com/resource/pubmed/chemical/Carbachol,
http://linkedlifedata.com/resource/pubmed/chemical/Cholinergic Agonists,
http://linkedlifedata.com/resource/pubmed/chemical/Potassium Chloride,
http://linkedlifedata.com/resource/pubmed/chemical/Protein Kinase Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Pyridines,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Y 27632,
http://linkedlifedata.com/resource/pubmed/chemical/rho-Associated Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/rhoA GTP-Binding Protein
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pubmed:status |
MEDLINE
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pubmed:issn |
1520-6777
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pubmed:author |
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pubmed:copyrightInfo |
(c) 2009 Wiley-Liss, Inc.
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pubmed:issnType |
Electronic
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
521-8
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pubmed:meshHeading |
pubmed-meshheading:19214992-Amides,
pubmed-meshheading:19214992-Animals,
pubmed-meshheading:19214992-Blotting, Western,
pubmed-meshheading:19214992-Carbachol,
pubmed-meshheading:19214992-Cholinergic Agonists,
pubmed-meshheading:19214992-Dose-Response Relationship, Drug,
pubmed-meshheading:19214992-Electric Stimulation,
pubmed-meshheading:19214992-Female,
pubmed-meshheading:19214992-Immunohistochemistry,
pubmed-meshheading:19214992-Muscle, Smooth,
pubmed-meshheading:19214992-Muscle Contraction,
pubmed-meshheading:19214992-Potassium Chloride,
pubmed-meshheading:19214992-Protein Kinase Inhibitors,
pubmed-meshheading:19214992-Pyridines,
pubmed-meshheading:19214992-RNA, Messenger,
pubmed-meshheading:19214992-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:19214992-Swine,
pubmed-meshheading:19214992-Urinary Bladder,
pubmed-meshheading:19214992-Urothelium,
pubmed-meshheading:19214992-rho-Associated Kinases,
pubmed-meshheading:19214992-rhoA GTP-Binding Protein
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pubmed:year |
2009
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pubmed:articleTitle |
Expression of RhoA mRNA and activated RhoA in urothelium and smooth muscle, and effects of a Rho-kinase inhibitor on contraction of the porcine urinary bladder.
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pubmed:affiliation |
Department of Urology, Dokkyo Medical University, Tochgi, Japan.
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pubmed:publicationType |
Journal Article,
In Vitro
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