Source:http://linkedlifedata.com/resource/pubmed/id/19209592
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
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| pubmed:dateCreated |
2009-2-12
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| pubmed:abstractText |
The oxidative reactivity of THF derivatives formed during THF/nC60 synthesis was evaluated with indigo dye as a model compound. The results showed that the formation of previously undetected oxidizing agents during THF/nC60 synthesis accounted for the degradation of indigo dye by THF/nC60 (THF/nC60/unwashed), while THF/nC60 after vigorous washing (THF/nC60/washed) and nC60 prepared without the use of THF were not reactive. gamma-Butyrolactone (GBL) was detected by GC-MS in the THF/nC60/unwashed as one of THF derivatives, but showed no reactivity with indigo dye. An organic peroxide was detected in the THF/nC60/unwashed by HPLC, and was reactive with indigo dye. This compound was found to also account for the elevated antibacterial and bactericidal activities of THF/nC60/unwashed on E. coli. Analysis by LC/(+ESI)MS and 1H NMR showed that the detected THF peroxide was tetrahydro-2-(tetrahydrofuran-2-ylperoxy)furan. The formation of THF peroxide during the preparation of aqueous stable C60 aggregates provides another potential explanation for the reactivity and oxidative stress mechanisms of THF/nC60 system reported in the literature, although it does not exclude the potential reactivity and toxicity of nC60 itself.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Anti-Bacterial Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Coloring Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Fullerenes,
http://linkedlifedata.com/resource/pubmed/chemical/Furans,
http://linkedlifedata.com/resource/pubmed/chemical/Indoles,
http://linkedlifedata.com/resource/pubmed/chemical/Peroxides,
http://linkedlifedata.com/resource/pubmed/chemical/Water,
http://linkedlifedata.com/resource/pubmed/chemical/indigo,
http://linkedlifedata.com/resource/pubmed/chemical/tetrahydrofuran
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| pubmed:status |
MEDLINE
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| pubmed:month |
Jan
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| pubmed:issn |
0013-936X
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:day |
1
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| pubmed:volume |
43
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
108-13
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| pubmed:meshHeading |
pubmed-meshheading:19209592-Anti-Bacterial Agents,
pubmed-meshheading:19209592-Bacteria,
pubmed-meshheading:19209592-Centrifugation,
pubmed-meshheading:19209592-Chromatography, Gas,
pubmed-meshheading:19209592-Chromatography, High Pressure Liquid,
pubmed-meshheading:19209592-Coloring Agents,
pubmed-meshheading:19209592-Escherichia coli,
pubmed-meshheading:19209592-Filtration,
pubmed-meshheading:19209592-Fullerenes,
pubmed-meshheading:19209592-Furans,
pubmed-meshheading:19209592-Indoles,
pubmed-meshheading:19209592-Kinetics,
pubmed-meshheading:19209592-Magnetic Resonance Spectroscopy,
pubmed-meshheading:19209592-Mass Spectrometry,
pubmed-meshheading:19209592-Microbial Sensitivity Tests,
pubmed-meshheading:19209592-Microbial Viability,
pubmed-meshheading:19209592-Oxidation-Reduction,
pubmed-meshheading:19209592-Peroxides,
pubmed-meshheading:19209592-Water
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| pubmed:year |
2009
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| pubmed:articleTitle |
Delineating oxidative processes of aqueous C60 preparations: role of THF peroxide.
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| pubmed:affiliation |
School of Civil and Environmental Engineering, Georgia Institute of Technology, 200 Bobby Dodd Way, Atlanta, Georgia 30332, USA.
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| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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