Linked Life Data

19201486

Source:http://linkedlifedata.com/resource/pubmed/id/19201486

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
2009-3-24
pubmed:abstractText
We conducted a prospective nested case-control study among military service members to investigate whether antibodies against tetanus or diphtheria predict multiple sclerosis (MS) risk. Paired T-tests were used to compare means of anti-tetanus and diphtheria toxoids among 56 MS cases and 112 matched controls. Conditional logistic regression was used to estimate odds ratios (OR). There were no differences between the mean serum IgG antibodies against tetanus (p-value 0.28) or diphtheria (p-value 0.45) in the baseline samples. The OR of MS associated with 1 standard deviation difference in antibody titers was 0.76 (95% CI: 0.48-1.21) for tetanus (SD=4.71) and 1.03 (0.73-1.45) for diphtheria (SD=0.87). Results of this study suggest serum IgG antibodies against tetanus or diphtheria are not predictors of MS risk.
pubmed:grant
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1872-8421
pubmed:author
pubmed:issnType
Electronic
pubmed:day
31
pubmed:volume
208
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
141-2
pubmed:dateRevised
2011-4-5
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Serum titers of IgG antibodies against tetanus and diphtheria toxoids and risk of multiple sclerosis.
pubmed:affiliation
Department of Nutrition, Harvard School of Public Health, Boston, MA, 02115, USA. jmassa@hsph.harvard.edu
pubmed:publicationType
Journal Article, Comparative Study, Research Support, N.I.H., Extramural