19198633

Source:http://linkedlifedata.com/resource/pubmed/id/19198633

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0003232, umls-concept:C0015576, umls-concept:C0080194, umls-concept:C0253479, umls-concept:C1295886, umls-concept:C2743850
pubmed:issue	2
pubmed:dateCreated	2009-2-26
pubmed:abstractText	Caboxamycin, a new benzoxazole antibiotic, was detected by HPLC-diode array screening in extracts of the marine strain Streptomyces sp. NTK 937, which was isolated from deep-sea sediment collected in the Canary Basin. The structure of caboxamycin was determined by mass spectrometry, NMR experiments and X-ray analysis. It showed inhibitory activity against Gram-positive bacteria, selected human tumor cell lines and the enzyme phosphodiesterase.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0151115
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Anti-Bacterial Agents, http://linkedlifedata.com/resource/pubmed/chemical/Antibiotics, Antineoplastic, http://linkedlifedata.com/resource/pubmed/chemical/Benzoxazoles
pubmed:status	MEDLINE
pubmed:month	Feb
pubmed:issn	0021-8820
pubmed:author	pubmed-author:BeilWinfriedW, pubmed-author:BrownRoselynR, pubmed-author:BruntnerChristinaC, pubmed-author:BullAlan TAT, pubmed-author:FiedlerHans-PeterHP, pubmed-author:GoodfellowMichaelM, pubmed-author:HohmannClaudiaC, pubmed-author:ImhoffJohannes FJF, pubmed-author:IrranElisabethE, pubmed-author:JonesAmanda LAL, pubmed-author:KrämerMarcoM, pubmed-author:NicholsonGraemeG, pubmed-author:SüssmuthRoderich DRD, pubmed-author:SchneiderKathrinK, pubmed-author:StachJames E MJE
pubmed:issnType	Print
pubmed:volume	62
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	99-104
pubmed:meshHeading	pubmed-meshheading:19198633-Anti-Bacterial Agents, pubmed-meshheading:19198633-Antibiotics, Antineoplastic, pubmed-meshheading:19198633-Benzoxazoles, pubmed-meshheading:19198633-Cell Line, Tumor, pubmed-meshheading:19198633-Cell Survival, pubmed-meshheading:19198633-Drug Evaluation, Preclinical, pubmed-meshheading:19198633-Drug Screening Assays, Antitumor, pubmed-meshheading:19198633-Fermentation, pubmed-meshheading:19198633-Gram-Positive Bacteria, pubmed-meshheading:19198633-Humans, pubmed-meshheading:19198633-Magnetic Resonance Spectroscopy, pubmed-meshheading:19198633-Microbial Sensitivity Tests, pubmed-meshheading:19198633-Models, Molecular, pubmed-meshheading:19198633-Molecular Conformation, pubmed-meshheading:19198633-Seawater, pubmed-meshheading:19198633-Spectrometry, Mass, Electrospray Ionization, pubmed-meshheading:19198633-Spectrophotometry, Infrared, pubmed-meshheading:19198633-Spectrophotometry, Ultraviolet, pubmed-meshheading:19198633-Streptomyces, pubmed-meshheading:19198633-Water Microbiology
pubmed:year	2009
pubmed:articleTitle	Caboxamycin, a new antibiotic of the benzoxazole family produced by the deep-sea strain Streptomyces sp. NTK 937.
pubmed:affiliation	Mikrobiologisches Institut, Universität Tübingen, Tübingen, Germany.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't