Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2009-2-24
pubmed:abstractText
The 3 gene products of the Na(+)/Ca(2+) exchanger (NCX), viz, NCX1, NCX2, and NCX3, may play a pivotal role in the pathophysiology of brain ischemia. The aim of this study was to investigate the transductional and posttranslational mechanisms involved in the expression of these isoforms during oxygen and glucose deprivation and their role in endoplasmic reticulum Ca(2+) refilling in cortical neurons.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1524-4628
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
40
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
922-9
pubmed:meshHeading
pubmed-meshheading:19164785-Animals, pubmed-meshheading:19164785-Blotting, Western, pubmed-meshheading:19164785-Calcium Signaling, pubmed-meshheading:19164785-Caspase 12, pubmed-meshheading:19164785-Cell Death, pubmed-meshheading:19164785-Cell Hypoxia, pubmed-meshheading:19164785-Cerebral Cortex, pubmed-meshheading:19164785-Endoplasmic Reticulum, pubmed-meshheading:19164785-Enzyme Activation, pubmed-meshheading:19164785-Female, pubmed-meshheading:19164785-Fluorescent Dyes, pubmed-meshheading:19164785-Fura-2, pubmed-meshheading:19164785-Glucose, pubmed-meshheading:19164785-NF-kappa B, pubmed-meshheading:19164785-Neurons, pubmed-meshheading:19164785-Pregnancy, pubmed-meshheading:19164785-RNA, Small Interfering, pubmed-meshheading:19164785-RNA Interference, pubmed-meshheading:19164785-Rats, pubmed-meshheading:19164785-Rats, Wistar, pubmed-meshheading:19164785-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:19164785-Sodium-Calcium Exchanger, pubmed-meshheading:19164785-Transcription Factor RelA, pubmed-meshheading:19164785-Up-Regulation
pubmed:year
2009
pubmed:articleTitle
Anoxia-induced NF-kappaB-dependent upregulation of NCX1 contributes to Ca2+ refilling into endoplasmic reticulum in cortical neurons.
pubmed:affiliation
Fondazione IRCCS SDN, Naples, Italy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't