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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2009-2-16
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pubmed:abstractText |
Initial high dose glucocorticosteroid (GC) treatment of transplant recipients induces changes in the glucocorticoid receptor (GR) that may affect the mode of action of the drug. We developed a TaqMan one-step RT-PCR quantification method to investigate the effect of bolus GC treatment on the structure of the GR complex by measuring the levels of GR isoform expression and FK binding protein 5 (FKBP5) transcription.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0966-3274
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
249-52
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pubmed:meshHeading |
pubmed-meshheading:19162184-Graft Rejection,
pubmed-meshheading:19162184-Haplotypes,
pubmed-meshheading:19162184-Humans,
pubmed-meshheading:19162184-Kidney Transplantation,
pubmed-meshheading:19162184-Length of Stay,
pubmed-meshheading:19162184-Leukocytes, Mononuclear,
pubmed-meshheading:19162184-Methylprednisolone,
pubmed-meshheading:19162184-Polymorphism, Single Nucleotide,
pubmed-meshheading:19162184-Predictive Value of Tests,
pubmed-meshheading:19162184-Protein Isoforms,
pubmed-meshheading:19162184-Receptors, Glucocorticoid,
pubmed-meshheading:19162184-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:19162184-Sensitivity and Specificity,
pubmed-meshheading:19162184-Tacrolimus Binding Proteins
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pubmed:year |
2009
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pubmed:articleTitle |
A novel method for monitoring glucocorticoid-induced changes of the glucocorticoid receptor in kidney transplant recipients.
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pubmed:affiliation |
University of Southern California, Los Angeles, CA, USA. chenyan@usc.edu
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pubmed:publicationType |
Journal Article
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