Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2009-1-22
pubmed:abstractText
Dementia can be caused by different diseases including Alzheimer's disease (AD), dementia with Lewy bodies (DLB), or both (AD + DLB). University of Kentucky AD Center pathologically-diagnosed AD and AD + DLB cases were evaluated who had three or more longitudinal antemortem mental status examinations (n = 156). Patients with important concomitant pathology (n = 5) or patients that were profoundly demented at recruitment (intake MMSE < 20; n = 86) were excluded to strengthen our ability to test the association of specific clinical and pathological indices. Patients with pathologically-diagnosed AD + DLB (n = 25) lost cognitive capacity faster than patients with AD alone (n = 40). In both diseases, treatment with acetylcholinesterase inhibitors was associated with a slower rate of cognitive decline.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/19158418-10844722, http://linkedlifedata.com/resource/pubmed/commentcorrection/19158418-10984725, http://linkedlifedata.com/resource/pubmed/commentcorrection/19158418-11217870, http://linkedlifedata.com/resource/pubmed/commentcorrection/19158418-11255450, http://linkedlifedata.com/resource/pubmed/commentcorrection/19158418-11723339, http://linkedlifedata.com/resource/pubmed/commentcorrection/19158418-12489913, http://linkedlifedata.com/resource/pubmed/commentcorrection/19158418-12754338, http://linkedlifedata.com/resource/pubmed/commentcorrection/19158418-1512391, http://linkedlifedata.com/resource/pubmed/commentcorrection/19158418-15985574, http://linkedlifedata.com/resource/pubmed/commentcorrection/19158418-16380608, http://linkedlifedata.com/resource/pubmed/commentcorrection/19158418-16401735, http://linkedlifedata.com/resource/pubmed/commentcorrection/19158418-16858742, http://linkedlifedata.com/resource/pubmed/commentcorrection/19158418-17159097, http://linkedlifedata.com/resource/pubmed/commentcorrection/19158418-17265415, http://linkedlifedata.com/resource/pubmed/commentcorrection/19158418-17727648, http://linkedlifedata.com/resource/pubmed/commentcorrection/19158418-18090922, http://linkedlifedata.com/resource/pubmed/commentcorrection/19158418-18289452, http://linkedlifedata.com/resource/pubmed/commentcorrection/19158418-9330994, http://linkedlifedata.com/resource/pubmed/commentcorrection/19158418-9710002, http://linkedlifedata.com/resource/pubmed/commentcorrection/19158418-9785144
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1387-2877
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
29-34
pubmed:dateRevised
2011-8-31
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Acetylcholinesterase inhibitor treatment is associated with relatively slow cognitive decline in patients with Alzheimer's disease and AD + DLB.
pubmed:affiliation
Department of Pathology, University of Kentucky Medical Center, University of Kentucky, Lexington, KY, USA. pnels2@email.uky.edu
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural