Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2009-3-12
pubmed:abstractText
Leg ulcers may result in serious morbidity in patients with connective tissue diseases and Raynaud's phenomenon (RP). We describe a 35-year-old woman with mixed connective tissue disease who suffered from leg ulcers refractory to iloprost. When the patient was treated with the selective endothelin A receptor antagonist sitaxsentan for pulmonary arterial hypertension, the ulcers improved within 4 weeks and resolved completely thereafter. In addition, severity of RP ameliorated markedly. Further evaluation of sitaxsentan in patients with connective tissue diseases suffering from ischemic skin ulcers is required.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1435-1250
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
68
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
154-6
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
[Leg ulcer in mixed connective tissue disease. Resolution during sitaxsentan therapy].
pubmed:affiliation
Medizinische Klinik und Poliklinik D, Universitätsklinikum Münster, Albert-Schweitzer-Str. 33, 48149 Münster. beckerhe@mednet.uni-muenster.de
pubmed:publicationType
Journal Article, English Abstract, Case Reports