Source:http://linkedlifedata.com/resource/pubmed/id/19156432
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2009-3-12
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pubmed:abstractText |
Leg ulcers may result in serious morbidity in patients with connective tissue diseases and Raynaud's phenomenon (RP). We describe a 35-year-old woman with mixed connective tissue disease who suffered from leg ulcers refractory to iloprost. When the patient was treated with the selective endothelin A receptor antagonist sitaxsentan for pulmonary arterial hypertension, the ulcers improved within 4 weeks and resolved completely thereafter. In addition, severity of RP ameliorated markedly. Further evaluation of sitaxsentan in patients with connective tissue diseases suffering from ischemic skin ulcers is required.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1435-1250
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
68
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
154-6
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pubmed:meshHeading |
pubmed-meshheading:19156432-Adult,
pubmed-meshheading:19156432-Antihypertensive Agents,
pubmed-meshheading:19156432-Female,
pubmed-meshheading:19156432-Humans,
pubmed-meshheading:19156432-Isoxazoles,
pubmed-meshheading:19156432-Leg Ulcer,
pubmed-meshheading:19156432-Raynaud Disease,
pubmed-meshheading:19156432-Scleroderma, Systemic,
pubmed-meshheading:19156432-Thiophenes,
pubmed-meshheading:19156432-Treatment Outcome
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pubmed:year |
2009
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pubmed:articleTitle |
[Leg ulcer in mixed connective tissue disease. Resolution during sitaxsentan therapy].
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pubmed:affiliation |
Medizinische Klinik und Poliklinik D, Universitätsklinikum Münster, Albert-Schweitzer-Str. 33, 48149 Münster. beckerhe@mednet.uni-muenster.de
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pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
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