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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2009-2-27
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pubmed:abstractText |
The precise role of gonadotropins in the carcinogenesis of epithelial ovarian cancer remains uncertain. Recently, the haplotype of two single nucleotide polymorphisms, Thr307Ala (rs6165) and Asn680Ser (rs6166), has been described as a risk factor for ovarian cancer in Chinese women. In this study we investigated the impact of this haplotype regarding the risk to develop ovarian cancer as well as possible effects upon the clinical course in a Caucasian patient sample.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1095-6859
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
112
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
486-9
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pubmed:meshHeading |
pubmed-meshheading:19147210-Adult,
pubmed-meshheading:19147210-Aged,
pubmed-meshheading:19147210-Aged, 80 and over,
pubmed-meshheading:19147210-Asian Continental Ancestry Group,
pubmed-meshheading:19147210-Case-Control Studies,
pubmed-meshheading:19147210-European Continental Ancestry Group,
pubmed-meshheading:19147210-Female,
pubmed-meshheading:19147210-Genotype,
pubmed-meshheading:19147210-Humans,
pubmed-meshheading:19147210-Middle Aged,
pubmed-meshheading:19147210-Ovarian Neoplasms,
pubmed-meshheading:19147210-Polymerase Chain Reaction,
pubmed-meshheading:19147210-Polymorphism, Single Nucleotide,
pubmed-meshheading:19147210-Receptors, FSH,
pubmed-meshheading:19147210-Retrospective Studies,
pubmed-meshheading:19147210-Risk Factors,
pubmed-meshheading:19147210-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
The haplotype of two FSHR polymorphisms in ovarian cancer--a potential role of ethnology in risk modification.
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pubmed:affiliation |
Institute of Pharmacogenetics, Medical Faculty, University of Duisburg-Essen, Germany. martin.heubner@uk-essen.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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