Linked Life Data

1914386

Source:http://linkedlifedata.com/resource/pubmed/id/1914386

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1991-11-6
pubmed:abstractText
The value of needle biopsy (NB) of pulmonary masses in patients unsuitable for surgery is well established. The presence of malignant cells confirms the diagnosis and thus aids management. We have reviewed 196 patients aged over 40 years with a solitary pulmonary mass suspected of being operable lung cancer to assess the effect of a negative NB result on the management. Malignant cells were discovered in 148 patients and diagnoses of infection were made in a further 10. In 38 patients no malignant cells were identified. Nineteen patients proceeded to thoracotomy and 13 of these had malignant disease. Nine others had further needle biopsies and eight of these had malignancy. Ten patients were followed up without any further intervention and four of these eventually proved to have malignancy. Thus of the 38 patients with no malignant cells on NB but no definite benign diagnosis, 25 had malignancy, six had benign disease and seven had presumed benign disease. In this series NB provided a definite benign diagnosis in 5.1% of patients. From this study it may be concluded that if a solitary pulmonary nodule has a high clinical suspicion of malignancy and the patient is a candidate for surgery, NB is of limited value in management.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0009-9260
pubmed:author
pubmed:issnType
Print
pubmed:volume
44
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
147-9
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
The value of negative needle biopsy in suspected operable lung cancer.
pubmed:affiliation
Department of Radiology, Royal Brompton National Heart and Lung Hospital, London.
pubmed:publicationType
Journal Article