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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1991-10-28
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pubmed:abstractText |
The first three human gene transfer/therapy clinical protocols are now underway after having been subjected to an extensive review process by the Recombinant DNA Advisory Committee (RAC) and its Human Gene Therapy Subcommittee. The "Points to Consider" document developed by the RAC established the framework for evaluating genetic intervention protocols. This review process is taking place in a broader social context. Public attitude surveys in this country have indicated a general lack of knowledge in the area of genetic engineering but an acceptance of somatic-cell gene therapy as treatment for disease. Internationally, numerous policy statements on human genetic intervention have been published, all of which support the moral legitimacy of somatic-cell gene therapy for the cure of disease. The debate over the ethical issues related to somatic-cell gene therapy has evolved over a ten-year-period. The time has now come to begin a formal public process for the ethical assessment of germ-line genetic intervention.
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pubmed:keyword |
http://linkedlifedata.com/resource/pubmed/keyword/Analytical Approach,
http://linkedlifedata.com/resource/pubmed/keyword/Genetics and Reproduction,
http://linkedlifedata.com/resource/pubmed/keyword/Human Gene Therapy Subcommittee,
http://linkedlifedata.com/resource/pubmed/keyword/NATIONAL INSTITUTES OF HEALTH,
http://linkedlifedata.com/resource/pubmed/keyword/Points to Consider: Transfer of...,
http://linkedlifedata.com/resource/pubmed/keyword/Recombinant DNA Advisory Committee
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pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
E
|
pubmed:status |
MEDLINE
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pubmed:issn |
1043-0342
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
2
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
115-22
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pubmed:dateRevised |
2005-11-16
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pubmed:meshHeading |
pubmed-meshheading:1911932-Advisory Committees,
pubmed-meshheading:1911932-Ethical Review,
pubmed-meshheading:1911932-Ethics, Medical,
pubmed-meshheading:1911932-Ethics Committees, Research,
pubmed-meshheading:1911932-Federal Government,
pubmed-meshheading:1911932-Gene Therapy,
pubmed-meshheading:1911932-Government Regulation,
pubmed-meshheading:1911932-Humans,
pubmed-meshheading:1911932-Internationality,
pubmed-meshheading:1911932-Public Policy,
pubmed-meshheading:1911932-Social Responsibility,
pubmed-meshheading:1911932-United States
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pubmed:year |
1991
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pubmed:articleTitle |
Human gene therapy: ethics and public policy.
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pubmed:affiliation |
Kennedy Institute of Ethics, Georgetown University, Washington, D.C. 20057.
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pubmed:publicationType |
Journal Article,
Review
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