pubmed:abstractText |
Various molecules participate in implantation and maintaining endometrial function during gestation. The remodeling of endometrial matrices is a necessary process in the coordination of gestational progress. Matrix-metalloproteinases (MMPs) like gelatinases (MMP-2 and -9) and collagenase (MMP-1) are considered to play important roles in this process. We examined MMP-2 and -9 expression using zymography, in situ hybridization, real-time PCR, and microarray analysis to clarify their roles in the bovine endometrium during gestation.
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pubmed:affiliation |
Laboratory of Veterinary Physiology, Department of Veterinary Medicine, Iwate University, Ueda 3-18-8, Morioka, Iwate 020-8550, Japan. kizaki@iwate-u.ac.jp
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