|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
8
|
|
pubmed:dateCreated |
2009-7-10
|
|
pubmed:abstractText |
Treatment of adult ovariectomized (OVX) rats with strontium ranelate prevented vertebral biomechanics degradation as a result of the prevention of bone loss and micro-architecture deterioration associated to an effect on intrinsic bone material quality. Strontium ranelate influenced the determinants of bone strength by prevention of ovariectomy-induced changes which contribute to explain strontium ranelate antifracture efficacy.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Aug
|
|
pubmed:issn |
1433-2965
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
20
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1417-28
|
|
pubmed:meshHeading |
pubmed-meshheading:19096745-Alkaline Phosphatase,
pubmed-meshheading:19096745-Amino Acids,
pubmed-meshheading:19096745-Animals,
pubmed-meshheading:19096745-Bone Density Conservation Agents,
pubmed-meshheading:19096745-Bone Remodeling,
pubmed-meshheading:19096745-Compressive Strength,
pubmed-meshheading:19096745-Disease Models, Animal,
pubmed-meshheading:19096745-Dose-Response Relationship, Drug,
pubmed-meshheading:19096745-Drug Evaluation, Preclinical,
pubmed-meshheading:19096745-Female,
pubmed-meshheading:19096745-Lumbar Vertebrae,
pubmed-meshheading:19096745-Organometallic Compounds,
pubmed-meshheading:19096745-Osteoporosis,
pubmed-meshheading:19096745-Ovariectomy,
pubmed-meshheading:19096745-Rats,
pubmed-meshheading:19096745-Rats, Sprague-Dawley,
pubmed-meshheading:19096745-Strontium,
pubmed-meshheading:19096745-Thiophenes,
pubmed-meshheading:19096745-X-Ray Microtomography
|
|
pubmed:year |
2009
|
|
pubmed:articleTitle |
Strontium ranelate improves bone strength in ovariectomized rat by positively influencing bone resistance determinants.
|
|
pubmed:affiliation |
Department Orthopaedics/Sports Medicine, University of Washington, Washington, USA. sdbain@u.washington.edu
|
|
pubmed:publicationType |
Journal Article
|
