rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2008-12-18
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pubmed:abstractText |
Schizophrenia is a complex disease with multiple factors contributing to its pathogenesis. In addition to environmental factors, genetic factors may also increase susceptibility. In other words, schizophrenia is a highly heritable disease. Some candidate genes have been deduced on the basis of their known function with others found on the basis of chromosomal location. Individuals with multiple candidate genes may have increased risk. However it is not clear what kind of gene combinations may produce the disease phenotype. Their collective effect remains to be studied.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19091023-10591225,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19091023-10802651,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19091023-11140673,
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2105
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
9 Suppl 12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
S23
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:19091023-Calcium Channels,
pubmed-meshheading:19091023-Cluster Analysis,
pubmed-meshheading:19091023-Computational Biology,
pubmed-meshheading:19091023-Genetic Predisposition to Disease,
pubmed-meshheading:19091023-Humans,
pubmed-meshheading:19091023-Nerve Tissue Proteins,
pubmed-meshheading:19091023-Neuregulin-1,
pubmed-meshheading:19091023-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:19091023-Pattern Recognition, Automated,
pubmed-meshheading:19091023-Phenotype,
pubmed-meshheading:19091023-Protein Interaction Mapping,
pubmed-meshheading:19091023-Risk Factors,
pubmed-meshheading:19091023-Schizophrenia,
pubmed-meshheading:19091023-Signal Transduction,
pubmed-meshheading:19091023-Synapses
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pubmed:year |
2008
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pubmed:articleTitle |
A protein interaction based model for schizophrenia study.
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pubmed:affiliation |
Institute of Biomedical Informatics, National Yang-Ming University, Taiwan. pchsu@ym.edu.tw
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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