Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2008-12-18
pubmed:abstractText
Protein kinases of the MARK family phosphorylate tau protein in its repeat domain and thereby regulate its affinity for microtubules and affect the aggregation of tau into Alzheimer paired helical filaments. We are searching for low molecular weight compounds to interfere with the activity of MARK and its pathways. Here we summarize structural features of MARK and cellular pathways of regulation.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-10069814, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-10542369, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-10662688, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-10830161, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-10830165, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-11089574, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-11837744, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-12079361, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-12429843, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-12431373, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-12471243, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-12639708, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-14517247, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-14976552, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-14981097, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-15084291, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-15324659, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-15450610, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-15563607, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-15705853, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-16014608, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-16472737, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-16717194, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-16803889, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-17047359, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-17075132, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-17360912, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-17716969, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-17726107, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-18199773, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-18424437, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-7706316, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-8003955, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-8612268, http://linkedlifedata.com/resource/pubmed/commentcorrection/19090997-9108484
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1471-2202
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
9 Suppl 2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S9
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Structure and regulation of MARK, a kinase involved in abnormal phosphorylation of Tau protein.
pubmed:affiliation
Max-Planck-Unit for Structural Molecular Biology, c/o DESY, Notkestrasse 85, Hamburg, Germany. timm@mpasmb.desy.de
pubmed:publicationType
Journal Article, Review