Linked Life Data

19089714

Source:http://linkedlifedata.com/resource/pubmed/id/19089714

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2008-12-17
pubmed:abstractText
The acute toxicity and changes in the activity of antioxidant enzymes including superoxide dismutase (SOD) and catalase (CAT) in the zebrafish Danio rerio were measured when the fish was exposed to paclobutrazol (PBZ) under laboratory conditions. The median lethal concentration value at 96 h post-exposure (LC(50) (96 h)) was determined to be 20.55 mg/L. In addition, the SOD activities in D. rerio were significantly higher at 96 h post-exposure among the various concentrations of the pollutant tested. The change of CAT activity could be considered as a sensitive biomarker of the oxidative stress induced by PBZ. The structure-activity relationship (SAR) analysis identified the potential active points for the pollutant and that the cavum may be the site of interaction with the receptor.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1532-4109
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
44
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
44-50
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Oxidative stress and structure-activity relationship in the zebrafish (Danio rerio) under exposure to paclobutrazol.
pubmed:affiliation
School of Environmental Science and Engineering, Shanghai Jiao Tong University, Shanghai, China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't