Source:http://linkedlifedata.com/resource/pubmed/id/19089540
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
2008-12-17
|
| pubmed:abstractText |
Small peptides including the Arg-Gly-Asp (RGD) motif have been used in studies on cell-extracellular matrix (ECM) attachment due to their ability to disturb integrin-mediated attachment on the cell surface. As another biological action of RGD peptides, several reports have shown that RGD peptides are incorporated into cytoplasm and induce apoptosis by direct activation of caspase-3. This study evaluated the effect of RGD peptides on chondrocytes and synovial cells and studied the involvement of caspases.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
0949-2658
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
13
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
524-32
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| pubmed:meshHeading |
pubmed-meshheading:19089540-Animals,
pubmed-meshheading:19089540-Apoptosis,
pubmed-meshheading:19089540-Caspase 3,
pubmed-meshheading:19089540-Cells, Cultured,
pubmed-meshheading:19089540-Chondrocytes,
pubmed-meshheading:19089540-Oligopeptides,
pubmed-meshheading:19089540-Osteoarthritis,
pubmed-meshheading:19089540-Rabbits,
pubmed-meshheading:19089540-Synovial Membrane
|
| pubmed:year |
2008
|
| pubmed:articleTitle |
RGD peptide-induced cell death of chondrocytes and synovial cells.
|
| pubmed:affiliation |
Department of Orthopaedic Surgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba 260-8677, Japan.
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| pubmed:publicationType |
Journal Article
|