Source:http://linkedlifedata.com/resource/pubmed/id/19087985
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2009-2-27
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pubmed:abstractText |
Drug resistance mechanisms can reduce response rate and duration in men with castration-resistant prostate cancer (CRPC) receiving docetaxel-based therapy. Patupilone (epothilone B), a microtubule-targeting agent, may be unaffected by some resistance mechanisms. Therefore, a phase II study assessed the patupilone safety and activity in CRPC patients with and without previous chemotherapy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1569-8041
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
492-7
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pubmed:dateRevised |
2009-8-10
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pubmed:meshHeading |
pubmed-meshheading:19087985-Aged,
pubmed-meshheading:19087985-Aged, 80 and over,
pubmed-meshheading:19087985-Antineoplastic Agents,
pubmed-meshheading:19087985-Epothilones,
pubmed-meshheading:19087985-Humans,
pubmed-meshheading:19087985-Male,
pubmed-meshheading:19087985-Middle Aged,
pubmed-meshheading:19087985-Orchiectomy,
pubmed-meshheading:19087985-Prostatic Neoplasms
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pubmed:year |
2009
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pubmed:articleTitle |
Phase II trial of weekly patupilone in patients with castration-resistant prostate cancer.
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pubmed:affiliation |
University of Maryland Greenebaum Cancer Center, Baltimore, MD 21201, USA. ahussain@som.umaryland.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Clinical Trial, Phase II
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