Source:http://linkedlifedata.com/resource/pubmed/id/19081025
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2008-12-16
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pubmed:abstractText |
Hypertonic saline (HTS) has been proposed as a resuscitation strategy following trauma based on its ability to prevent organ dysfunction by exerting immunosuppressive effects on inflammatory cells, including neutrophils. Because these cells are central to the innate response to bacteria, we hypothesized that hypertonic treatment for hemorrhagic shock might alter the host response to bacterial contamination of the peritoneal cavity and therefore render the host more susceptible to invasive infection.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1532-7361
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
144
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
814-21
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pubmed:meshHeading |
pubmed-meshheading:19081025-Animals,
pubmed-meshheading:19081025-Escherichia coli Infections,
pubmed-meshheading:19081025-Male,
pubmed-meshheading:19081025-Neutrophil Infiltration,
pubmed-meshheading:19081025-Peritoneal Cavity,
pubmed-meshheading:19081025-Plasma Substitutes,
pubmed-meshheading:19081025-Pseudomonas Infections,
pubmed-meshheading:19081025-Rats,
pubmed-meshheading:19081025-Rats, Sprague-Dawley,
pubmed-meshheading:19081025-Resuscitation,
pubmed-meshheading:19081025-Saline Solution, Hypertonic,
pubmed-meshheading:19081025-Shock, Hemorrhagic
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pubmed:year |
2008
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pubmed:articleTitle |
Hypertonic saline resuscitation from hemorrhagic shock does not impair the neutrophil response to intraabdominal infection.
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pubmed:affiliation |
Department of Surgery, St Michael's Hospital and University of Toronto, and the Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Ontario, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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