Source:http://linkedlifedata.com/resource/pubmed/id/19041704
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2009-1-2
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pubmed:abstractText |
Various species of Hypericum genus have been used in the Canary Islands as sedative, diuretic, vermifuge, wound healing, antihysteric and antidepressant agent. Studies have shown that methanol extract of Hypericum grandifolium Choisy is active in tetrabenazine-induced ptosis and forced swimming tests. In the current study, the aqueous, butanol and chloroform fractions obtained from the methanol extract as well as three sub-fractions derived from the chloroform fraction were evaluated for their central nervous effects in mice, particularly their antidepressant activity.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0378-8741
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
21
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pubmed:volume |
121
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
297-303
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pubmed:meshHeading |
pubmed-meshheading:19041704-Animals,
pubmed-meshheading:19041704-Antidepressive Agents,
pubmed-meshheading:19041704-Behavior, Animal,
pubmed-meshheading:19041704-Body Temperature,
pubmed-meshheading:19041704-Depression,
pubmed-meshheading:19041704-Disease Models, Animal,
pubmed-meshheading:19041704-Hypericum,
pubmed-meshheading:19041704-Male,
pubmed-meshheading:19041704-Medicine, Traditional,
pubmed-meshheading:19041704-Mice,
pubmed-meshheading:19041704-Motor Activity,
pubmed-meshheading:19041704-Plant Components, Aerial,
pubmed-meshheading:19041704-Plant Extracts,
pubmed-meshheading:19041704-Spain,
pubmed-meshheading:19041704-Swimming
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pubmed:year |
2009
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pubmed:articleTitle |
Hypericum grandifolium Choisy: a species native to Macaronesian Region with antidepressant effect.
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pubmed:affiliation |
Departamento de Farmacología, Facultad de Farmacia, Universidad de La Laguna, c/Astrofísico Francisco Sánchez s/n, 38071 La Laguna, Tenerife, Spain. csanchez@ull.es
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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