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rdf:type |
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lifeskim:mentions |
umls-concept:C0002210,
umls-concept:C0035647,
umls-concept:C0036536,
umls-concept:C0036537,
umls-concept:C0117719,
umls-concept:C0449258,
umls-concept:C0808232,
umls-concept:C0851285,
umls-concept:C1159816,
umls-concept:C1514485,
umls-concept:C1521840,
umls-concept:C1882932,
umls-concept:C2239176
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pubmed:issue |
1
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pubmed:dateCreated |
2008-12-3
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pubmed:abstractText |
FGFR4, a member of the fibroblast growth factor receptor family, has been recently associated with progression of melanoma, breast and head and neck carcinoma. Given its uniquely high expression in the liver, we investigated its contributory role to hepatocellular carcinoma (HCC).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/FGF19 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/FGFR4 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Fibroblast Growth Factors,
http://linkedlifedata.com/resource/pubmed/chemical/PD 173074,
http://linkedlifedata.com/resource/pubmed/chemical/Pyrimidines,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Fibroblast Growth...,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Fibroblast Growth Factor,
http://linkedlifedata.com/resource/pubmed/chemical/alpha-Fetoproteins
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0168-8278
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
118-27
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:19008009-Antineoplastic Agents,
pubmed-meshheading:19008009-Apoptosis,
pubmed-meshheading:19008009-Carcinoma, Hepatocellular,
pubmed-meshheading:19008009-Case-Control Studies,
pubmed-meshheading:19008009-Cell Proliferation,
pubmed-meshheading:19008009-Disease Progression,
pubmed-meshheading:19008009-Fibroblast Growth Factors,
pubmed-meshheading:19008009-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:19008009-Humans,
pubmed-meshheading:19008009-Liver,
pubmed-meshheading:19008009-Liver Neoplasms,
pubmed-meshheading:19008009-Polymorphism, Single Nucleotide,
pubmed-meshheading:19008009-Pyrimidines,
pubmed-meshheading:19008009-Receptor, Fibroblast Growth Factor, Type 4,
pubmed-meshheading:19008009-Receptors, Fibroblast Growth Factor,
pubmed-meshheading:19008009-alpha-Fetoproteins
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pubmed:year |
2009
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pubmed:articleTitle |
Fibroblast growth factor receptor 4 regulates proliferation, anti-apoptosis and alpha-fetoprotein secretion during hepatocellular carcinoma progression and represents a potential target for therapeutic intervention.
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pubmed:affiliation |
Singapore OncoGenome Laboratory, Institute of Medical Biology, A *STAR, 8A Biomedical Grove, #06-06 Immunos, Singapore 138648, Singapore. hankiat.ho@imb.a-star.edu.sg
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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